Filing Flows › Repligen (RGEN) › Q4 2025
Repligen (RGEN) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 26, 2026
Repligen (RGEN) reported revenue of $198M for the fourth quarter 2025 (Q4 2025), +18% from a year earlier and +5% from the quarter before. Operating margin was 9.0%, net earnings $13.3M (6.7% of revenue).
Repligen, Q4 2025: revenue $198M (+18% year over year), operating margin 9.0%, net earnings $13.3M, operating cash flow $25.7M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $198M | +5% | +18% |
| Operating profit | $17.9M | +6% | — |
| Net earnings | $13.3M | -11% | — |
| Operating cash flow | $25.7M | -47% | -34% |
| Free cash flow | $17.6M | -60% | -48% |
What changed
Revenue was $197.9M in Q4 2025, up 18% year over year and up 5% from the previous quarter. Product was the largest line at 100% of revenue.
Operating profit was $17.9M, a 9.0% margin (up 30.8 points year over year). Total costs fell 12% while revenue rose 18%. Net earnings were $13.3M. The effective tax rate was 30.5%.
Operating cash flow was $25.7M (down 34% year over year), 193% of net earnings. Non-cash charges added back $20.0M of depreciation and amortization and $8.0M of share-based compensation. Working capital and other items used $15.5M. Capital expenditures of $8.2M left free cash flow of $17.6M.
Questions
What was Repligen's revenue in the fourth quarter 2025?
Repligen (RGEN) reported revenue of $198M for the fourth quarter 2025 (Q4 2025), +18% from a year earlier and +5% from the quarter before.
Was Repligen profitable in the fourth quarter 2025?
Operating profit was $17.9M (9.0% of revenue) and net earnings $13.3M.
Source: Repligen 10-K on SEC EDGAR.