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Regenxbio (RGNX) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

Regenxbio (RGNX) reported revenue of $21.4M for the second quarter 2025 (Q2 2025), -4% from a year earlier and -76% from the quarter before. Operating margin was -296.3%, net loss $70.9M (331.8% of revenue).

Revenue$21.4M
Year over year-4%
Quarter over quarter-76%
Operating margin-296.3%
Net earnings−$70.9M

Regenxbio, Q2 2025: revenue $21.4M (-4% year over year), operating margin -296.3%, net loss $70.9M, operating cash flow −$49.3M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$21.4M-76%-4%
Operating profit−$63.3M-622%—
Net earnings−$70.9M-1265%—
Operating cash flow−$49.3M-247%—

What changed

Revenue was $21.4M in Q2 2025, down 4% year over year and down 76% from the previous quarter. License and Service was the largest line at 86% of revenue. License and Service lost $3.4M year over year (down 15%), 361% of the total change.

Operating costs exceeded revenue by $63.3M, an operating margin of -296.3%. Total costs grew 8% against a revenue fall of 4%. The fastest-growing cost line was Research & development (+22%). The quarter ended with a net loss of $70.9M, after a profit of $6.1M the previous quarter.

Operating cash flow was −$49.3M. Non-cash charges added back $3.9M of depreciation and amortization and $8.7M of share-based compensation. Working capital and other items added $9.0M. Capital expenditures of $391K exceeded it, leaving free cash flow of −$49.7M.

Questions

What was Regenxbio's revenue in the second quarter 2025?

Regenxbio (RGNX) reported revenue of $21.4M for the second quarter 2025 (Q2 2025), -4% from a year earlier and -76% from the quarter before.

Was Regenxbio profitable in the second quarter 2025?

Operating loss was $63.3M (-296.3% of revenue) and net loss $70.9M.

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Source: Regenxbio 10-Q on SEC EDGAR.