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Rigel Pharmaceuticals (RIGL) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 3, 2026

Rigel Pharmaceuticals (RIGL) reported revenue of $69.8M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and +0.5% from the quarter before. Operating margin was 33.2%, net earnings $268M (384.0% of revenue).

Revenue$69.8M
Year over year+21%
Quarter over quarter+0.5%
Operating margin33.2%
Net earnings$268M

Rigel Pharmaceuticals, Q4 2025: revenue $69.8M (+21% year over year), operating margin 33.2%, net earnings $268M, operating cash flow $22.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$69.8M+0.5%+21%
Operating profit$23.2M-18%+39%
Net earnings$268M+861%19×
Operating cash flow$22.0M-9%+52%

What changed

Revenue was $69.8M in Q4 2025, up 21% year over year and roughly flat from the previous quarter. Product sales, net was the largest line at 94% of revenue.

Operating profit was $23.2M, a 33.2% margin (up 4.3 points year over year). Of the extra revenue versus a year earlier, 53% reached operating profit, above the 29% margin then. Total costs grew 14% against revenue growth of 21%. The fastest-growing cost line was Research & development (+90%). Net earnings were $268.1M, up 1769% year over year. The tax line was a benefit of $245.4M on pre-tax earnings of $22.7M.

Operating cash flow was $22.0M (up 52% year over year), 8% of net earnings. Non-cash charges added back $601K of depreciation and amortization and $2.7M of share-based compensation. Working capital and other items used $249.4M. Capital expenditures of −$12K left free cash flow of $22.0M.

Questions

What was Rigel Pharmaceuticals' revenue in the fourth quarter 2025?

Rigel Pharmaceuticals (RIGL) reported revenue of $69.8M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and +0.5% from the quarter before.

Was Rigel Pharmaceuticals profitable in the fourth quarter 2025?

Operating profit was $23.2M (33.2% of revenue) and net earnings $268M.

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Source: Rigel Pharmaceuticals 10-K on SEC EDGAR.