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Relay Therapeutics (RLAY) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 26, 2026

Relay Therapeutics (RLAY) reported revenue of $7.0M for the fourth quarter 2025 (Q4 2025). Operating margin was -866.1%, net loss $54.9M (784.1% of revenue).

Revenue$7.0M
Year over year—
Quarter over quarter—
Operating margin-866.1%
Net earnings−$54.9M

Relay Therapeutics, Q4 2025: revenue $7.0M, operating margin -866.1%, net loss $54.9M, operating cash flow −$44.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$7.0M——
Operating profit−$60.6M——
Net earnings−$54.9M——
Operating cash flow−$44.9M——

What changed

Revenue was $7.0M in Q4 2025.

Operating costs exceeded revenue by $60.6M, an operating margin of -866.1%. The quarter ended with a net loss of $54.9M.

Operating cash flow was −$44.9M. Non-cash charges added back $599K of depreciation and $13.1M of share-based compensation. Working capital and other items used $3.6M. Capital expenditures of $1K exceeded it, leaving free cash flow of −$44.9M.

Questions

What was Relay Therapeutics' revenue in the fourth quarter 2025?

Relay Therapeutics (RLAY) reported revenue of $7.0M for the fourth quarter 2025 (Q4 2025).

Was Relay Therapeutics profitable in the fourth quarter 2025?

Operating loss was $60.6M (-866.1% of revenue) and net loss $54.9M.

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Source: Relay Therapeutics 10-K on SEC EDGAR.