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Royalty Pharma (RPRX) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 11, 2026

Royalty Pharma (RPRX) reported revenue of $622M for the fourth quarter 2025 (Q4 2025), +5% from a year earlier and +2% from the quarter before. Operating margin was 62.4%, net earnings $215M (34.6% of revenue).

Revenue$622M
Year over year+5%
Quarter over quarter+2%
Operating margin62.4%
Net earnings$215M

Royalty Pharma, Q4 2025: revenue $622M (+5% year over year), operating margin 62.4%, net earnings $215M, operating cash flow $827M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$622M+2%+5%
Operating profit$388M-9%+7%
Net earnings$215M-24%+3%
Operating cash flow$827M+18%+11%

What changed

Revenue was $622.0M in Q4 2025, up 5% year over year and up 2% from the previous quarter. Income from financial royalty assets was the largest line at 95% of revenue.

Operating profit was $388.4M, a 62.4% margin (up 1.5 points year over year). Of the extra revenue versus a year earlier, 95% reached operating profit, above the 61% margin then. Total costs grew 1% against revenue growth of 5%. The fastest-growing cost line was Research & development (+10000%). Net earnings were $215.2M, up 3% year over year. The effective tax rate was 0.0%.

Operating cash flow was $827.1M (up 11% year over year), 232% of net income including minority interests. Non-cash charges added back $1.2M of depreciation and $125.8M of share-based compensation. Working capital and other items added $343.3M.

Questions

What was Royalty Pharma's revenue in the fourth quarter 2025?

Royalty Pharma (RPRX) reported revenue of $622M for the fourth quarter 2025 (Q4 2025), +5% from a year earlier and +2% from the quarter before.

Was Royalty Pharma profitable in the fourth quarter 2025?

Operating profit was $388M (62.4% of revenue) and net earnings $215M.

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Source: Royalty Pharma 10-K on SEC EDGAR.