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Scilex Holding (SCLX) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 13, 2025

Scilex Holding (SCLX) reported revenue of $9.9M for the second quarter 2025 (Q2 2025), -40% from a year earlier and +98% from the quarter before. Operating margin was -207.2%, net loss $44.0M (445.1% of revenue).

Revenue$9.9M
Year over year-40%
Quarter over quarter+98%
Operating margin-207.2%
Net earnings−$44.0M

Scilex Holding, Q2 2025: revenue $9.9M (-40% year over year), operating margin -207.2%, net loss $44.0M, operating cash flow $7.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$9.9M+98%-40%
Operating profit−$20.5M——
Net earnings−$44.0M——
Operating cash flow$7.0M+17%+205%

What changed

Revenue was $9.9M in Q2 2025, down 40% year over year and up 98% from the previous quarter.

Operating costs exceeded revenue by $20.5M, an operating margin of -207.2%. Total costs fell 5% while revenue fell 40%. The fastest-growing cost line was Research & development (+209%). The quarter ended with a net loss of $44.0M, wider than the previous quarter's $26.1M loss. Net interest and other expense of $23.5M was the main reason.

Operating cash flow was $7.0M (up 205% year over year). Non-cash charges added back $1.0M of depreciation and amortization and $3.3M of share-based compensation. Working capital and other items added $46.8M.

Questions

What was Scilex Holding's revenue in the second quarter 2025?

Scilex Holding (SCLX) reported revenue of $9.9M for the second quarter 2025 (Q2 2025), -40% from a year earlier and +98% from the quarter before.

Was Scilex Holding profitable in the second quarter 2025?

Operating loss was $20.5M (-207.2% of revenue) and net loss $44.0M.

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Source: Scilex Holding 10-Q on SEC EDGAR.