Filing Flows › Scilex Holding (SCLX) › Q4 2025
Scilex Holding (SCLX) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Apr 10, 2026
Scilex Holding (SCLX) reported revenue of $4.8M for the fourth quarter 2025 (Q4 2025), -68% from a year earlier and -55% from the quarter before.
Scilex Holding, Q4 2025: revenue $4.8M (-68% year over year), net loss $46.1M, operating cash flow −$17.5M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $4.8M | -55% | -68% |
| Operating profit | −$111M | — | — |
| Net earnings | −$46.1M | — | — |
| Operating cash flow | −$17.5M | -312% | -789% |
What changed
Revenue was $4.8M in Q4 2025, down 68% year over year and down 55% from the previous quarter.
Operating costs exceeded revenue by $111.1M, an operating margin of -2317.8%. Total costs grew 168% against a revenue fall of 68%. The fastest-growing cost line was Other operating costs (+7387%). The quarter ended with a net loss of $46.1M, narrower than the previous quarter's $257.8M loss. Non-operating items added $65.0M, -141% of pre-tax earnings, so the bottom line overstates operating performance.
Operating cash flow was −$17.5M. Non-cash charges added back $1.6M of depreciation and amortization and $5.6M of share-based compensation. Working capital and other items added $21.4M.
Questions
What was Scilex Holding's revenue in the fourth quarter 2025?
Scilex Holding (SCLX) reported revenue of $4.8M for the fourth quarter 2025 (Q4 2025), -68% from a year earlier and -55% from the quarter before.
Source: Scilex Holding 10-K on SEC EDGAR.