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Scynexis (SCYX) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 4, 2026

Scynexis (SCYX) reported revenue of $18.6M for the fourth quarter 2025 (Q4 2025), up 19-fold from a year earlier and up 56-fold from the quarter before. Operating margin was 56.4%, net earnings $12.3M (65.7% of revenue).

Revenue$18.6M
Year over year19×
Quarter over quarter56×
Operating margin56.4%
Net earnings$12.3M

Scynexis, Q4 2025: revenue $18.6M (19× year over year), operating margin 56.4%, net earnings $12.3M, operating cash flow $18.4M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$18.6M56×19×
Operating profit$10.5M——
Net earnings$12.3M——
Operating cash flow$18.4M——

What changed

Revenue was $18.6M in Q4 2025, up 1808% year over year and up 5483% from the previous quarter.

Operating profit was $10.5M, a 56.4% margin (up 880.7 points year over year). Total costs fell 10% while revenue rose 1808%. Net earnings were $12.3M. The effective tax rate was 0.0%.

Operating cash flow was $18.4M, 150% of net earnings. Non-cash charges added back $687K of share-based compensation. Working capital and other items added $5.5M.

Questions

What was Scynexis' revenue in the fourth quarter 2025?

Scynexis (SCYX) reported revenue of $18.6M for the fourth quarter 2025 (Q4 2025), up 19-fold from a year earlier and up 56-fold from the quarter before.

Was Scynexis profitable in the fourth quarter 2025?

Operating profit was $10.5M (56.4% of revenue) and net earnings $12.3M.

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Source: Scynexis 10-K on SEC EDGAR.