Filing Flows › Septerna (SEPN) › Q1 2026 › vs Q1 2025
Septerna (SEPN) Q1 2026 vs Q1 2025 (year over year)
Septerna's revenue rose $26.3M (121×) from $219K in Q1 2025 to $26.5M in Q1 2026.
Septerna, Q1 2026: revenue $26.5M (121× year over year), operating margin -50.1%, net loss $8.6M, operating cash flow −$25.6M. The chart draws each line against Q1 2025, the increases inside each band.
Every line
| Line | Q1 2026 | Q1 2025 | Change | % |
|---|---|---|---|---|
| Revenue | $26.5M | $219K | $26.3M | 121× |
| Other income, net | $5.0M | $4.4M | $566K | +13% |
| Net loss | $8.6M | $21.5M | −$12.8M | -60% |
| Costs & expenses | $40.2M | $26.1M | $14.0M | +54% |
| Operating costs | $39.8M | $26.1M | $13.7M | +52% |
| Income tax | $337K | $0 | $337K | — |
| Research & development | $29.5M | $19.3M | $10.3M | +53% |
| General & admin | $10.3M | $6.9M | $3.4M | +50% |
| Operating cash sources | $32.1M | $25.2M | $6.8M | +27% |
| Depreciation & amortization | $421K | $397K | $24K | +6% |
| Share-based compensation | $6.0M | $1.5M | $4.5M | +306% |
| Cash used in operations | $25.6M | $23.3M | $2.3M | +10% |
| Net loss absorbed | $8.6M | $21.5M | −$12.8M | -60% |
| Working capital & other | $23.4M | $3.7M | $19.7M | +526% |
Questions
How much did Septerna's revenue grow year over year in Q1 2026?
Septerna's revenue rose $26.3M (121×) from $219K in Q1 2025 to $26.5M in Q1 2026.