Filing Flows › Sera Prognostics (SERA) › Q4 2025
Sera Prognostics (SERA) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 18, 2026
Sera Prognostics (SERA) reported revenue of $10K for the fourth quarter 2025 (Q4 2025), -58% from a year earlier and -38% from the quarter before.
Sera Prognostics, Q4 2025: revenue $10K (-58% year over year), net loss $7.9M, operating cash flow −$6.1M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $10K | -38% | -58% |
| Operating profit | −$9.0M | — | — |
| Net earnings | −$7.9M | — | — |
| Operating cash flow | −$6.1M | — | — |
What changed
Revenue was $10K in Q4 2025, down 58% year over year and down 38% from the previous quarter.
Operating costs exceeded revenue by $9.0M, an operating margin of -89540.0%. Total costs fell 5% while revenue fell 58%. The fastest-growing cost line was Cost of revenue (+31%). The quarter ended with a net loss of $7.9M, wider than the previous quarter's $7.8M loss.
Operating cash flow was −$6.1M. Non-cash charges added back $244K of depreciation and amortization and $1.0M of share-based compensation. Working capital and other items added $498K. Capital expenditures of $330K exceeded it, leaving free cash flow of −$6.5M.
Questions
What was Sera Prognostics' revenue in the fourth quarter 2025?
Sera Prognostics (SERA) reported revenue of $10K for the fourth quarter 2025 (Q4 2025), -58% from a year earlier and -38% from the quarter before.
Source: Sera Prognostics 10-K on SEC EDGAR.