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ARS Pharmaceuticals (SPRY) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 9, 2026

ARS Pharmaceuticals (SPRY) reported revenue of $28.1M for the fourth quarter 2025 (Q4 2025), -68% from a year earlier and -14% from the quarter before. Operating margin was -147.6%, net loss $41.3M (147.1% of revenue).

Revenue$28.1M
Year over year-68%
Quarter over quarter-14%
Operating margin-147.6%
Net earnings−$41.3M

ARS Pharmaceuticals, Q4 2025: revenue $28.1M (-68% year over year), operating margin -147.6%, net loss $41.3M, operating cash flow −$43.5M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$28.1M-14%-68%
Operating profit−$41.5M——
Net earnings−$41.3M——
Operating cash flow−$43.5M——

What changed

Revenue was $28.1M in Q4 2025, down 68% year over year and down 14% from the previous quarter. Product was the largest line at 72% of revenue.

Operating costs exceeded revenue by $41.5M, an operating margin of -147.6%. Total costs grew 77% against a revenue fall of 68%. The fastest-growing cost line was Other operating costs (+611%). The quarter ended with a net loss of $41.3M, narrower than the previous quarter's $51.2M loss.

Operating cash flow was −$43.5M. Non-cash charges added back $417K of depreciation and amortization and $5.7M of share-based compensation. Working capital and other items used $8.3M.

Questions

What was ARS Pharmaceuticals' revenue in the fourth quarter 2025?

ARS Pharmaceuticals (SPRY) reported revenue of $28.1M for the fourth quarter 2025 (Q4 2025), -68% from a year earlier and -14% from the quarter before.

Was ARS Pharmaceuticals profitable in the fourth quarter 2025?

Operating loss was $41.5M (-147.6% of revenue) and net loss $41.3M.

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Source: ARS Pharmaceuticals 10-K on SEC EDGAR.