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Sarepta Therapeutics (SRPT) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 6, 2025

Sarepta Therapeutics (SRPT) reported revenue of $611M for the second quarter 2025 (Q2 2025), +68% from a year earlier and -18% from the quarter before. Operating margin was 18.9%, net earnings $197M (32.2% of revenue).

Revenue$611M
Year over year+68%
Quarter over quarter-18%
Operating margin18.9%
Net earnings$197M

Sarepta Therapeutics, Q2 2025: revenue $611M (+68% year over year), operating margin 18.9%, net earnings $197M, operating cash flow $261M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$611M-18%+68%
Gross profit$361M-24%+14%
Operating profit$116M——
Net earnings$197M—30×
Operating cash flow$261M—17×
Free cash flow$230M——

What changed

Revenue was $611.1M in Q2 2025, up 68% year over year and down 18% from the previous quarter. Elevidys was the largest line at 46% of revenue. Elevidys added $160.1M year over year (up 132%), 65% of the total change. Pmo Products declined 3%.

Gross margin was 59.0%, down 28.1 points from a year earlier. Operating profit was $115.6M, a 18.9% margin (up 19.1 points year over year). Operating expenses fell 23% while revenue rose 68%. Net earnings were $196.9M, up 2948% year over year. The effective tax rate was -28.2%. Non-operating items added $38.1M, 25% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $261.3M (up 1649% year over year), 133% of net earnings. Non-cash charges added back $10.8M of depreciation and amortization and $37.0M of share-based compensation. Working capital and other items added $16.6M. Capital expenditures of $31.8M left free cash flow of $229.5M.

Questions

What was Sarepta Therapeutics' revenue in the second quarter 2025?

Sarepta Therapeutics (SRPT) reported revenue of $611M for the second quarter 2025 (Q2 2025), +68% from a year earlier and -18% from the quarter before.

Was Sarepta Therapeutics profitable in the second quarter 2025?

Operating profit was $116M (18.9% of revenue) and net earnings $197M.

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Source: Sarepta Therapeutics 10-Q on SEC EDGAR.