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Starling Oncology (STLN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 12, 2026

Starling Oncology (STLN) reported revenue of $142M for the fourth quarter 2025 (Q4 2025), +42% from a year earlier and +4% from the quarter before. Operating margin was -4.9%, net loss $7.5M (5.3% of revenue).

Revenue$142M
Year over year+42%
Quarter over quarter+4%
Operating margin-4.9%
Net earnings−$7.5M

Starling Oncology, Q4 2025: revenue $142M (+42% year over year), operating margin -4.9%, net loss $7.5M, operating cash flow $3.2M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$142M+4%+42%
Operating profit−$6.9M——
Net earnings−$7.5M——
Operating cash flow$3.2M—-19%
Free cash flow$2.2M—-3%

What changed

Revenue was $142.0M in Q4 2025, up 42% year over year and up 4% from the previous quarter.

Operating costs exceeded revenue by $6.9M, an operating margin of -4.9%. Total costs grew 33% against revenue growth of 42%. The fastest-growing cost line was Other operating costs (+38%). The quarter ended with a net loss of $7.5M, narrower than the previous quarter's $16.5M loss.

Operating cash flow was $3.2M (down 19% year over year). Non-cash charges added back $1.6M of depreciation and amortization and $1.3M of share-based compensation. Working capital and other items added $7.8M. Capital expenditures of $1.1M left free cash flow of $2.2M.

Questions

What was Starling Oncology's revenue in the fourth quarter 2025?

Starling Oncology (STLN) reported revenue of $142M for the fourth quarter 2025 (Q4 2025), +42% from a year earlier and +4% from the quarter before.

Was Starling Oncology profitable in the fourth quarter 2025?

Operating loss was $6.9M (-4.9% of revenue) and net loss $7.5M.

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Source: Starling Oncology 10-K on SEC EDGAR.