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Stoke Therapeutics (STOK) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 7, 2026

Stoke Therapeutics (STOK) reported revenue of $6.2M for the first quarter 2026 (Q1 2026), -96% from a year earlier and +344% from the quarter before. Operating margin was -857.6%, net loss $50.0M (802.7% of revenue).

Revenue$6.2M
Year over year-96%
Quarter over quarter+344%
Operating margin-857.6%
Net earnings−$50.0M

Stoke Therapeutics, Q1 2026: revenue $6.2M (-96% year over year), operating margin -857.6%, net loss $50.0M, operating cash flow −$60.6M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$6.2M+344%-96%
Operating profit−$53.4M—-148%
Net earnings−$50.0M—-144%
Operating cash flow−$60.6M—-146%

What changed

Revenue was $6.2M in Q1 2026, down 96% year over year and up 344% from the previous quarter.

Operating costs exceeded revenue by $53.4M, an operating margin of -857.6%. Total costs grew 26% against a revenue fall of 96%. The fastest-growing cost line was SG&A (+36%). The quarter ended with a net loss of $50.0M, narrower than the previous quarter's $57.9M loss.

Operating cash flow was −$60.6M. Non-cash charges added back $439K of depreciation and $8.8M of share-based compensation. Working capital and other items used $19.8M. Capital expenditures of $353K exceeded it, leaving free cash flow of −$60.9M.

Questions

What was Stoke Therapeutics' revenue in the first quarter 2026?

Stoke Therapeutics (STOK) reported revenue of $6.2M for the first quarter 2026 (Q1 2026), -96% from a year earlier and +344% from the quarter before.

Was Stoke Therapeutics profitable in the first quarter 2026?

Operating loss was $53.4M (-857.6% of revenue) and net loss $50.0M.

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Source: Stoke Therapeutics 10-Q on SEC EDGAR.