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Supernus Pharmaceuticals (SUPN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 2, 2026

Supernus Pharmaceuticals (SUPN) reported revenue of $212M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and +10% from the quarter before. Operating margin was -1.9%, net loss $4.1M (1.9% of revenue).

Revenue$212M
Year over year+21%
Quarter over quarter+10%
Operating margin-1.9%
Net earnings−$4.1M

Supernus Pharmaceuticals, Q4 2025: revenue $212M (+22% year over year), operating margin -1.9%, net loss $4.1M, operating cash flow $19.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$212M+10%+21%
Operating profit−$3.9M——
Net earnings−$4.1M——
Operating cash flow$19.9M—-55%
Free cash flow$19.4M—-56%

What changed

Revenue was $211.6M in Q4 2025, up 21% year over year and up 10% from the previous quarter. Qelbree was the largest line at 38% of revenue.

Operating costs exceeded revenue by $3.9M, an operating margin of -1.9%. Total costs grew 41% against revenue growth of 21%. The fastest-growing cost line was Other operating costs (+127%). The quarter ended with a net loss of $4.1M, narrower than the previous quarter's $45.1M loss. Non-operating items added $2.0M, -106% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $19.9M (down 55% year over year). Non-cash charges added back $25.0M of depreciation and amortization and $9.7M of share-based compensation. Working capital and other items used $10.7M. Capital expenditures of $427K left free cash flow of $19.4M.

Questions

What was Supernus Pharmaceuticals' revenue in the fourth quarter 2025?

Supernus Pharmaceuticals (SUPN) reported revenue of $212M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and +10% from the quarter before.

Was Supernus Pharmaceuticals profitable in the fourth quarter 2025?

Operating loss was $3.9M (-1.9% of revenue) and net loss $4.1M.

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Source: Supernus Pharmaceuticals 10-K on SEC EDGAR.