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Tempus AI (TEM) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 24, 2026

Tempus AI (TEM) reported revenue of $367M for the fourth quarter 2025 (Q4 2025), +83% from a year earlier and +10% from the quarter before. Operating margin was -16.7%, net loss $54.2M (14.8% of revenue).

Revenue$367M
Year over year+83%
Quarter over quarter+10%
Operating margin-16.7%
Net earnings−$54.2M

Tempus AI, Q4 2025: revenue $367M (+83% year over year), operating margin -16.7%, net loss $54.2M, operating cash flow −$36.8M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$367M+10%+83%
Operating profit−$61.4M——
Net earnings−$54.2M——
Operating cash flow−$36.8M——

What changed

Revenue was $367.2M in Q4 2025, up 83% year over year and up 10% from the previous quarter.

Operating costs exceeded revenue by $61.4M, an operating margin of -16.7%. Total costs grew 71% against revenue growth of 83%. The fastest-growing cost line was SG&A (+87%). The quarter ended with a net loss of $54.2M, narrower than the previous quarter's $80.0M loss.

Operating cash flow was −$36.8M. Non-cash charges added back $7.7M of depreciation and $45.3M of share-based compensation. Working capital and other items used $35.7M. Capital expenditures of $4.8M exceeded it, leaving free cash flow of −$41.5M.

Questions

What was Tempus AI's revenue in the fourth quarter 2025?

Tempus AI (TEM) reported revenue of $367M for the fourth quarter 2025 (Q4 2025), +83% from a year earlier and +10% from the quarter before.

Was Tempus AI profitable in the fourth quarter 2025?

Operating loss was $61.4M (-16.7% of revenue) and net loss $54.2M.

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Source: Tempus AI 10-K on SEC EDGAR.