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Tango Therapeutics (TNGX) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 4, 2025

Tango Therapeutics (TNGX) reported revenue of $53.8M for the third quarter 2025 (Q3 2025), +364% from a year earlier and up 17-fold from the quarter before. Operating margin was 26.2%, net earnings $15.9M (29.5% of revenue).

Revenue$53.8M
Year over year+364%
Quarter over quarter17×
Operating margin26.2%
Net earnings$15.9M

Tango Therapeutics, Q3 2025: revenue $53.8M (+364% year over year), operating margin 26.2%, net earnings $15.9M, operating cash flow −$31.0M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$53.8M17×+364%
Operating profit$14.1M——
Net earnings$15.9M——
Operating cash flow−$31.0M——

What changed

Revenue was $53.8M in Q3 2025, up 364% year over year and up 1592% from the previous quarter.

Operating profit was $14.1M, a 26.2% margin (up 309.4 points year over year). Total costs fell 11% while revenue rose 364%. Net earnings were $15.9M. The effective tax rate was -0.1%.

Operating cash flow was −$31.0M. Non-cash charges added back $555K of depreciation and $6.6M of share-based compensation. Working capital and other items used $54.0M. Capital expenditures of $151K exceeded it, leaving free cash flow of −$31.1M.

Questions

What was Tango Therapeutics' revenue in the third quarter 2025?

Tango Therapeutics (TNGX) reported revenue of $53.8M for the third quarter 2025 (Q3 2025), +364% from a year earlier and up 17-fold from the quarter before.

Was Tango Therapeutics profitable in the third quarter 2025?

Operating profit was $14.1M (26.2% of revenue) and net earnings $15.9M.

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Source: Tango Therapeutics 10-Q on SEC EDGAR.