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Entrada Therapeutics (TRDA) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 8, 2025

Entrada Therapeutics (TRDA) reported revenue of $20.6M for the first quarter 2025 (Q1 2025), -65% from a year earlier and -45% from the quarter before. Operating margin was -106.0%, net loss $17.3M (84.4% of revenue).

Revenue$20.6M
Year over year-65%
Quarter over quarter-45%
Operating margin-106.0%
Net earnings−$17.3M

Entrada Therapeutics, Q1 2025: revenue $20.6M (-65% year over year), operating margin -106.0%, net loss $17.3M, operating cash flow −$38.5M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$20.6M-45%-65%
Operating profit−$21.8M——
Net earnings−$17.3M——
Operating cash flow−$38.5M——

What changed

Revenue was $20.6M in Q1 2025, down 65% year over year and down 45% from the previous quarter.

Operating costs exceeded revenue by $21.8M, an operating margin of -106.0%. Total costs grew 11% against a revenue fall of 65%. The fastest-growing cost line was Research & development (+12%). The quarter ended with a net loss of $17.3M, after a profit of $1.1M the previous quarter. Non-operating items added $4.4M, -26% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$38.5M. Non-cash charges added back $946K of depreciation and $5.1M of share-based compensation. Working capital and other items used $27.2M. Capital expenditures of $1.1M exceeded it, leaving free cash flow of −$39.7M.

Questions

What was Entrada Therapeutics' revenue in the first quarter 2025?

Entrada Therapeutics (TRDA) reported revenue of $20.6M for the first quarter 2025 (Q1 2025), -65% from a year earlier and -45% from the quarter before.

Was Entrada Therapeutics profitable in the first quarter 2025?

Operating loss was $21.8M (-106.0% of revenue) and net loss $17.3M.

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Source: Entrada Therapeutics 10-Q on SEC EDGAR.