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Tvardi Therapeutics (TVRD) earnings and revenue breakdown

Latest: Q1 2025 · 10-Q filed May 13, 2025 · Tvardi Therapeutics (TVRD) Q1 2025 earnings results →

Q1 2025 Revenue up 20% year over year to $2.6M · 191¢ of every $1 of revenue lost · operating margin -92.9%

Tvardi Therapeutics made $2.6M in Q1 2025 (+20% Y/Y): Other revenue $1.3M, Collaborative revenue $1.2M, Clinical compound revenue $48K. Operating margin -92.9%, net loss $4.9M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed May 13, 2025.

Revenue$2.6M
Year over year+20%
Operating margin-92.9%
Net earnings−$4.9M
Operating cash flow−$4.7M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $2.6M in Q1 2025, up 20% year over year and up 77% from the previous quarter. Other revenue was the largest line at 51% of revenue. Other revenue added $700K year over year (up 112%), 161% of the total change. Clinical compound revenue declined 43%.

Operating costs exceeded revenue by $2.4M, an operating margin of -92.9%. Total costs fell 84% while revenue rose 20%. The quarter ended with a net loss of $4.9M, narrower than the previous quarter's $7.7M loss. Net interest and other expense of $2.5M was the main reason.

Operating cash flow was −$4.7M. Non-cash charges added back $1.4M of share-based compensation. Working capital and other items used $1.2M.

Quarterly history

Tvardi Therapeutics revenue by quarterTvardi Therapeutics revenue by quarter$1.5MQ4 2024$2.6MQ1 2025
Tvardi Therapeutics net earnings by quarterTvardi Therapeutics net earnings by quarter−$7.7MQ4 2024−$4.9MQ1 2025
QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q1 202510-QMay 13, 2025$2.6M+20%-92.9%−$4.9M−$4.7M
Q4 202410-KMar 11, 2025$1.5M-52%-372.7%−$7.7M−$4.0M

Charts

Tvardi Therapeutics: where the cash came from (+) and went (−), TTM to Q2 2026Tvardi Therapeutics: where the cash came from (+) and went (−), TTM to Q2 2026Operating cash flow−$25.0MOther investing$20.5MCash drawn (+) / kept (−)$4.9MNot reconciled−$321K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Tvardi Therapeutics: profit against cash, quarter by quarterTvardi Therapeutics: profit against cash, quarter by quarterNet incomeOperating cash flow−$5.5M−$6.7MQ3 2024−$12.7M−$4.8MQ4 2024−$9.6M−$7.7MQ1 2025$4.2M−$5.9MQ2 2025−$5.5M−$4.3MQ3 2025−$7.3M−$5.7MQ4 2025−$6.8M−$5.9MQ1 2026−$6.5M−$9.2MQ2 2026
Latest (Q2 2026): Net income −$6.5M, Operating cash flow −$9.2M.
Tvardi Therapeutics: diluted shares by fiscal year (split-adjusted)Tvardi Therapeutics: diluted shares by fiscal year (split-adjusted)144MFY2020152MFY202113MFY202214MFY20238MFY20248MFY2025
-94.6% since FY2020: buybacks shrank the count; earlier years scaled for the 3-for-1 split before FY2025.
Tvardi Therapeutics in its industry: growth against margin (225 companies, SIC 2834)Tvardi Therapeutics in its industry: growth against margin (225 companies, SIC 2834)revenue growth, year over year →↑ operating marginmedian +11%median -50%JNJLLYMRKABBVPFEBMYABTREGNTEVAVTRSVRTXBHCZTSONCOGNALNYELANJAZZBMRNPRGOAMRXUTHRRPRXNRIXINSMKeenova Therapeutics plcALKSMDGLPAHCSRPTPTCTINDVBBIOACADCORTPBHANIPKNSAPTGXHRMYIONSAXSMTGTXSUPNTVTXCOLLVREOFAMPHMIRMPCRXRARELQDAARQTIRWDARDXNATRXNCREBSZLABXERSINVACRMDMNKDRYTMURGNPHATAUPHSNDXRIGLLGNDEOLSARWRPGENHROWVNDAOPKSDGRGERNETONAGIOPBYITNGXCYRXCYTKMRVIORGONUVBLFVNSIGAKROSAMRNZVRASPRYHRTXAKBABCYCKPTIGYREMGNXELTPSEPNVRDNLFCRCrinetics Pharmaceuticals, Inc.VSTMKURATBPHLABADCTNAMSFBIOXLODERMARCTRMTIAYTUFHTXENTATNXPOCULASMBWVEAPMDBFRIABEOSTOKLXRXCAPRIDYANKTRZOMDFINBPJANXSBFMGOSSETSTRCUSCPIXLIFDCUEAQSTPRAXWHWKVERUEMMAGENBVRCACELUQUREZYMEEQABCLIMNMKYNBAKTSRNACVSICNTBTRAWISCOEVFMLPCNCAMPAtaiBeckley Inc.CTMXALMSPMHSACRSVTGNROIVKRROJAGXENSCKRSAABUSPRPHSTTKCPHITRDATXMDGOVXNWBOBIOEUPBIRDOVIDSPRBXBIOPRTAMCRBARVNMNOVSLNIGCBIOALGVNDNTHCPMDSPRORFLCOYASCYXBFRGSXTPBTAIQHCWBSERYARWRNACRGBPAVTXCLNNNTHIHINDAAGHALTONCOCRVOSKVIBOLTBDPTLYELIBOPULMTVRD (+20%, -93%)
Pharmaceutical Preparations; dot size is quarterly revenue; dashed lines are the industry's medians.

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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About Tvardi Therapeutics

We are a clinical-stage biopharmaceutical company focused on the development of novel, oral, small molecule therapies targeting Signal Transducer and Activator of Transcription 3 (STAT3) to treat inflammatory and proliferative diseases with significant unmet need. Based upon our founders ’ seminal work and deep understanding of the transcription factor STAT3, we have designed an innovative approach to directly inhibit STAT3, a highly validated, yet historically undruggable target. Leveraging this expertise, we are developing a pipeline of STAT3 inhibitors with a differentiated mechanism of action and convenient oral dosing.

In its own words, from its 10-K, filed Mar 31, 2026.

Tvardi Therapeutics against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Revenue growth: +20% against the peers' median +10%. Operating margin: -92.9% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
TVRD Tvardi TherapeuticsQ1 2025$2.6M+20%-92.9%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Tvardi Therapeutics 10-Q on SEC EDGAR · CIK 1346830 · Pharmaceutical Preparations

13F: who owns TVRD and who is buying

Largest holders of TVRD (13F)Largest holders of TVRD (13F)Vanguard Group$1.8MSlate Path Capital LP$1.3MVanguard Capital Management LLC$654KAmerican Financial Group$425KUBS Group AG$211KSilvercrest Asset Management Grou…$192KBlackRock$181KRenaissance Technologies LLC$174KGeode Capital Management, LLC$172KMorgan Stanley$148K
Funds' net buying of TVRD by quarter (13F)Funds' net buying of TVRD by quarter (13F)$43.7M2025-06$26.4M2025-09$877K2025-12−$295K2026-03−$859K2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on TVRD

History

Every quarter: Q1 2025 results · Q4 2024 results

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