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Is Twist Bioscience (TWST) a takeover target?

A leveraged buyout does not work for Twist Bioscience on its latest figures: it has no positive EBITDA to borrow against (−$120M over the last 12 months, on revenue of $432M).

Share price$159.78
Market value$10.0B
Enterprise value$9.8B
Cash$167M
Debt$0
Revenue, 12 months$432M
Revenue growth+19%
EBITDA, 12 months−$120M

Why a leveraged buyout does not fit

A leveraged buyout is paid for mostly with debt that the company's own cash flow repays. Twist Bioscience's EBITDA over the last 12 months was −$120M on revenue of $432M, so there is nothing to lend against and nothing to repay a loan with: a buyer would have to pay almost entirely with its own money. That is the kind of deal another company — a strategic buyer that wants the products, the pipeline or the technology — makes, not a private-equity fund. The model therefore gives no buyout price.

What a takeover could cost

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Twist Bioscience would cost about $215.70 a share, $13.5B for all its shares.

Premium%Price a shareAll shares
Low end (a quarter of deals paid less)22%$194.93$12.2B
Median35%$215.70$13.5B
High end (a quarter paid more)45%$231.68$14.5B

Twist Bioscience's latest quarter

Twist Bioscience, Q3 FY26: revenue $118M (+23% year over year), operating margin -30.6%, net loss $35.1M, operating cash flow $1.1M. The chart follows the revenue to costs, profit and cash.

Questions

Is Twist Bioscience being acquired?

No headline, 8-K or 13D about a sale is on file in the last year.

Could private equity buy Twist Bioscience?

A leveraged buyout does not work for Twist Bioscience on its latest figures: it has no positive EBITDA to borrow against (−$120M over the last 12 months, on revenue of $432M). With no cash flow to repay a loan, a buyer would pay almost entirely with its own money: a deal for another company (a strategic buyer), not for a private-equity fund.

What would a takeover of Twist Bioscience cost?

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Twist Bioscience would cost about $215.70 a share, $13.5B for all its shares.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.