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10x Genomics (TXG) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 8, 2026

10x Genomics (TXG) reported revenue of $151M for the first quarter 2026 (Q1 2026), -3% from a year earlier and -9% from the quarter before. Operating margin was -11.3%, net loss $13.5M (8.9% of revenue).

Revenue$151M
Year over year-3%
Quarter over quarter-9%
Operating margin-11.3%
Net earnings−$13.5M

10x Genomics, Q1 2026: revenue $151M (-3% year over year), operating margin -11.3%, net loss $13.5M, operating cash flow $26.1M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$151M-9%-3%
Operating profit−$17.0M——
Net earnings−$13.5M——
Operating cash flow$26.1M-36%-24%
Free cash flow$24.5M-37%-24%

What changed

Revenue was $150.8M in Q1 2026, down 3% year over year and down 9% from the previous quarter. Single Cell was the largest line at 59% of revenue. License and royalty revenue lost $16.1M year over year (down 94%), 399% of the total change.

Gross margin was 70.4%, up 2.3 points from Q1 2025. Operating costs exceeded revenue by $17.0M, an operating margin of -11.3%. Operating expenses fell 15% while revenue fell 3%. The quarter ended with a net loss of $13.5M, narrower than the previous quarter's $16.3M loss. Non-operating items added $4.2M, -33% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $26.1M (down 24% year over year). Non-cash charges added back $10.0M of depreciation and amortization and $22.6M of share-based compensation. Working capital and other items added $7.0M. Capital expenditures of $1.6M left free cash flow of $24.5M.

Questions

What was 10x Genomics' revenue in the first quarter 2026?

10x Genomics (TXG) reported revenue of $151M for the first quarter 2026 (Q1 2026), -3% from a year earlier and -9% from the quarter before.

Was 10x Genomics profitable in the first quarter 2026?

Operating loss was $17.0M (-11.3% of revenue) and net loss $13.5M.

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Source: 10x Genomics 10-Q on SEC EDGAR.