Filing Flows › Upstream Bio (UPB) › Q2 2026 › vs Q1 2026
Upstream Bio (UPB) Q2 2026 vs Q1 2026 (quarter over quarter)
Upstream Bio's revenue fell $261K (-25%) from $1.0M in Q1 2026 to $773K in Q2 2026.
Upstream Bio, Q2 2026: revenue $773K (-18% year over year), net loss $39.7M, operating cash flow −$35.6M. The chart draws each line against Q1 2026, the increases inside each band.
Every line
| Line | Q2 2026 | Q1 2026 | Change | % |
|---|---|---|---|---|
| Revenue | $773K | $1.0M | −$261K | -25% |
| Other income, net | $2.7M | $3.0M | −$358K | -12% |
| Net loss | $39.7M | $40.6M | −$889K | -2% |
| Costs & expenses | $43.1M | $44.6M | −$1.5M | -3% |
| Operating costs | $43.1M | $44.6M | −$1.5M | -3% |
| Research & development | $36.1M | $36.6M | −$476K | -1% |
| General & admin | $7.1M | $8.1M | −$1.0M | -13% |
| Operating cash sources | $40.0M | $52.5M | −$12.5M | -24% |
| Depreciation & amortization | $50K | $49K | $1K | +2% |
| Share-based compensation | $4.4M | $4.6M | −$293K | -6% |
| Cash used in operations | $35.6M | $47.9M | −$12.2M | -26% |
| Net loss absorbed | $39.7M | $40.6M | −$889K | -2% |
| Working capital & other | $323K | $12.0M | −$11.6M | -97% |
Questions
How much did Upstream Bio's revenue grow quarter over quarter in Q2 2026?
Upstream Bio's revenue fell $261K (-25%) from $1.0M in Q1 2026 to $773K in Q2 2026.