Filing Flows › Upstream Bio (UPB) › Q2 2026 › vs Q2 2025
Upstream Bio (UPB) Q2 2026 vs Q2 2025 (year over year)
Upstream Bio's revenue fell $164K (-18%) from $937K in Q2 2025 to $773K in Q2 2026.
Upstream Bio, Q2 2026: revenue $773K (-18% year over year), net loss $39.7M, operating cash flow −$35.6M. The chart draws each line against Q2 2025, the increases inside each band.
Every line
| Line | Q2 2026 | Q2 2025 | Change | % |
|---|---|---|---|---|
| Revenue | $773K | $937K | −$164K | -18% |
| Other income, net | $2.7M | $4.4M | −$1.7M | -39% |
| Net loss | $39.7M | $40.0M | −$264K | -0.7% |
| Costs & expenses | $43.1M | $45.3M | −$2.1M | -5% |
| Operating costs | $43.1M | $45.3M | −$2.1M | -5% |
| Research & development | $36.1M | $37.9M | −$1.8M | -5% |
| General & admin | $7.1M | $7.4M | −$367K | -5% |
| Operating cash sources | $40.0M | $41.9M | −$1.9M | -4% |
| Depreciation & amortization | $50K | $42K | $8K | +19% |
| Share-based compensation | $4.4M | $2.6M | $1.8M | +68% |
| Cash used in operations | $35.6M | $39.2M | −$3.6M | -9% |
| Net loss absorbed | $39.7M | $40.0M | −$264K | -0.7% |
| Working capital & other | $323K | $1.9M | −$1.6M | -83% |
Questions
How much did Upstream Bio's revenue grow year over year in Q2 2026?
Upstream Bio's revenue fell $164K (-18%) from $937K in Q2 2025 to $773K in Q2 2026.