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Vir Biotechnology (VIR) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 23, 2026

Vir Biotechnology (VIR) reported revenue of $64.1M for the fourth quarter 2025 (Q4 2025), +418% from a year earlier and up 267-fold from the quarter before. Operating margin was -74.8%, net loss $42.9M (67.0% of revenue).

Revenue$64.1M
Year over year+418%
Quarter over quarter267×
Operating margin-74.8%
Net earnings−$42.9M

Vir Biotechnology, Q4 2025: revenue $64.1M (+418% year over year), operating margin -74.8%, net loss $42.9M, operating cash flow −$25.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$64.1M267×+418%
Operating profit−$47.9M——
Net earnings−$42.9M——
Operating cash flow−$25.9M——

What changed

Revenue was $64.1M in Q4 2025, up 418% year over year and up 26596% from the previous quarter.

Operating costs exceeded revenue by $47.9M, an operating margin of -74.8%. Total costs fell 14% while revenue rose 418%. The quarter ended with a net loss of $42.9M, narrower than the previous quarter's $163.1M loss.

Operating cash flow was −$25.9M. Non-cash charges added back $2.9M of depreciation and amortization and $11.2M of share-based compensation. Working capital and other items added $2.9M. Capital expenditures of $348K exceeded it, leaving free cash flow of −$26.2M.

Questions

What was Vir Biotechnology's revenue in the fourth quarter 2025?

Vir Biotechnology (VIR) reported revenue of $64.1M for the fourth quarter 2025 (Q4 2025), +418% from a year earlier and up 267-fold from the quarter before.

Was Vir Biotechnology profitable in the fourth quarter 2025?

Operating loss was $47.9M (-74.8% of revenue) and net loss $42.9M.

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Source: Vir Biotechnology 10-K on SEC EDGAR.