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Vertex Pharmaceuticals (VRTX) Q2 2026 earnings results (second quarter 2026)

10-Q filed Aug 4, 2026

Vertex Pharmaceuticals (VRTX) reported revenue of $3.3B for the second quarter 2026 (Q2 2026), +12% from a year earlier and +12% from the quarter before. Operating margin was 37.4%, net earnings $1.1B (33.0% of revenue).

Revenue$3.3B
Year over year+12%
Quarter over quarter+12%
Operating margin37.4%
Net earnings$1.1B

Vertex Pharmaceuticals, Q2 2026: revenue $3.3B (+12% year over year), operating margin 37.4%, net earnings $1.1B, operating cash flow $1.1B. The chart follows the revenue to costs, profit and cash.

Q2 2026AmountQ/QY/Y
Revenue$3.3B+12%+12%
Operating profit$1.2B+10%+8%
Net earnings$1.1B+7%+6%
Operating cash flow$1.1B-21%+5%
Free cash flow$1.0B-22%+9%

What changed

Revenue was $3.3B in Q2 2026, up 12% year over year and up 12% from the previous quarter. TRIKAFTA/KAFTRIO was the largest line at 75% of revenue. ALYFTREK added $0.42B year over year (up 266%), 113% of the total change. Other CF product revenues declined 29%.

Operating profit was $1.2B, a 37.4% margin (down 1.4 points year over year). Of the extra revenue versus Q2 2025, 26% reached operating profit, below the 39% margin then. Total costs grew 15% against revenue growth of 12%. The fastest-growing cost line was SG&A (+37%). Net earnings were $1.1B, up 6% year over year. The effective tax rate was 21.0%.

Operating cash flow was $1.1B (up 5% year over year), 102% of net earnings. Non-cash charges added back $0.06B of depreciation and amortization and $0.17B of share-based compensation. Working capital and other items used $0.20B. Capital expenditures of $0.11B left free cash flow of $1.0B.

Questions

What was Vertex Pharmaceuticals' revenue in the second quarter 2026?

Vertex Pharmaceuticals (VRTX) reported revenue of $3.3B for the second quarter 2026 (Q2 2026), +12% from a year earlier and +12% from the quarter before.

Was Vertex Pharmaceuticals profitable in the second quarter 2026?

Operating profit was $1.2B (37.4% of revenue) and net earnings $1.1B.

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Source: Vertex Pharmaceuticals 10-Q on SEC EDGAR.