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Verastem (VSTM) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 4, 2026

Verastem (VSTM) reported revenue of $17.5M for the fourth quarter 2025 (Q4 2025) and +56% from the quarter before. Operating margin was -236.5%, net loss $32.9M (187.7% of revenue).

Revenue$17.5M
Year over year—
Quarter over quarter+56%
Operating margin-236.5%
Net earnings−$32.9M

Verastem, Q4 2025: revenue $17.5M, operating margin -236.5%, net loss $32.9M, operating cash flow −$30.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$17.5M+56%—
Operating profit−$41.5M——
Net earnings−$32.9M——
Operating cash flow−$30.0M——

What changed

Revenue was $17.5M in Q4 2025, up 56% from the previous quarter.

Operating costs exceeded revenue by $41.5M, an operating margin of -236.5%. The quarter ended with a net loss of $32.9M, narrower than the previous quarter's $98.5M loss. Non-operating items added $8.6M, -26% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$30.0M. Non-cash charges added back $298K of depreciation and amortization and $2.0M of share-based compensation.

Questions

What was Verastem's revenue in the fourth quarter 2025?

Verastem (VSTM) reported revenue of $17.5M for the fourth quarter 2025 (Q4 2025) and +56% from the quarter before.

Was Verastem profitable in the fourth quarter 2025?

Operating loss was $41.5M (-236.5% of revenue) and net loss $32.9M.

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Source: Verastem 10-K on SEC EDGAR.