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Vaxart (VXRT) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 13, 2026

Vaxart (VXRT) reported revenue of $104M for the fourth quarter 2025 (Q4 2025), +586% from a year earlier and +44% from the quarter before. Operating margin was 53.2%, net earnings $55.0M (52.8% of revenue).

Revenue$104M
Year over year+586%
Quarter over quarter+44%
Operating margin53.2%
Net earnings$55.0M

Vaxart, Q4 2025: revenue $104M (+586% year over year), operating margin 53.2%, net earnings $55.0M, operating cash flow $30.7M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$104M+44%+586%
Operating profit$55.4M——
Net earnings$55.0M——
Operating cash flow$30.7M12×—
Free cash flow$30.7M12×—

What changed

Revenue was $104.2M in Q4 2025, up 586% year over year and up 44% from the previous quarter.

Operating profit was $55.4M, a 53.2% margin (up 128.8 points year over year). Total costs grew 83% against revenue growth of 586%. The fastest-growing cost line was Research & development (+99%). Net earnings were $55.0M. The effective tax rate was 0.6%.

Operating cash flow was $30.7M, 56% of net earnings. Non-cash charges added back $2.1M of depreciation and amortization and $1.7M of share-based compensation. Working capital and other items used $28.2M. Capital expenditures of $1K left free cash flow of $30.7M.

Questions

What was Vaxart's revenue in the fourth quarter 2025?

Vaxart (VXRT) reported revenue of $104M for the fourth quarter 2025 (Q4 2025), +586% from a year earlier and +44% from the quarter before.

Was Vaxart profitable in the fourth quarter 2025?

Operating profit was $55.4M (53.2% of revenue) and net earnings $55.0M.

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Source: Vaxart 10-K on SEC EDGAR.