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Voyager Therapeutics (VYGR) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 9, 2026

Voyager Therapeutics (VYGR) reported revenue of $15.3M for the fourth quarter 2025 (Q4 2025), +144% from a year earlier and +15% from the quarter before. Operating margin was -195.2%, net loss $27.4M (178.8% of revenue).

Revenue$15.3M
Year over year+144%
Quarter over quarter+15%
Operating margin-195.2%
Net earnings−$27.4M

Voyager Therapeutics, Q4 2025: revenue $15.3M (+144% year over year), operating margin -195.2%, net loss $27.4M, operating cash flow −$30.3M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$15.3M+15%+144%
Operating profit−$29.9M——
Net earnings−$27.4M——
Operating cash flow−$30.3M——

What changed

Revenue was $15.3M in Q4 2025, up 144% year over year and up 15% from the previous quarter.

Operating costs exceeded revenue by $29.9M, an operating margin of -195.2%. Total costs grew 2% against revenue growth of 144%. The quarter ended with a net loss of $27.4M, narrower than the previous quarter's $27.9M loss.

Operating cash flow was −$30.3M. Non-cash charges added back $1.0M of depreciation and $3.5M of share-based compensation. Working capital and other items used $7.4M. Capital expenditures of $626K exceeded it, leaving free cash flow of −$30.9M.

Questions

What was Voyager Therapeutics' revenue in the fourth quarter 2025?

Voyager Therapeutics (VYGR) reported revenue of $15.3M for the fourth quarter 2025 (Q4 2025), +144% from a year earlier and +15% from the quarter before.

Was Voyager Therapeutics profitable in the fourth quarter 2025?

Operating loss was $29.9M (-195.2% of revenue) and net loss $27.4M.

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Source: Voyager Therapeutics 10-K on SEC EDGAR.