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Wave Life Sciences (WVE) Q2 2025 earnings results (second quarter 2025)

10-Q filed Jul 30, 2025

Wave Life Sciences (WVE) reported revenue of $8.7M for the second quarter 2025 (Q2 2025), -56% from a year earlier and -5% from the quarter before. Operating margin was -606.5%, net loss $50.5M (580.2% of revenue).

Revenue$8.7M
Year over year-56%
Quarter over quarter-5%
Operating margin-606.5%
Net earnings−$50.5M

Wave Life Sciences, Q2 2025: revenue $8.7M (-56% year over year), operating margin -606.5%, net loss $50.5M, operating cash flow −$46.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$8.7M-5%-56%
Operating profit−$52.8M——
Net earnings−$50.5M——
Operating cash flow−$46.0M——

What changed

Revenue was $8.7M in Q2 2025, down 56% year over year and down 5% from the previous quarter.

Operating costs exceeded revenue by $52.8M, an operating margin of -606.5%. Total costs grew 12% against a revenue fall of 56%. The fastest-growing cost line was General & admin (+26%). The quarter ended with a net loss of $50.5M, wider than the previous quarter's $46.9M loss.

Operating cash flow was −$46.0M. Non-cash charges added back $865K of depreciation and $6.2M of share-based compensation. Working capital and other items used $2.6M. Capital expenditures of $306K exceeded it, leaving free cash flow of −$46.3M.

Questions

What was Wave Life Sciences' revenue in the second quarter 2025?

Wave Life Sciences (WVE) reported revenue of $8.7M for the second quarter 2025 (Q2 2025), -56% from a year earlier and -5% from the quarter before.

Was Wave Life Sciences profitable in the second quarter 2025?

Operating loss was $52.8M (-606.5% of revenue) and net loss $50.5M.

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Source: Wave Life Sciences 10-Q on SEC EDGAR.