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Xenon Pharmaceuticals (XENE) earnings and revenue breakdown

Latest: Q1 2025 · 10-Q filed May 12, 2025 · Xenon Pharmaceuticals (XENE) Q1 2025 earnings results →

Q1 2025 867¢ of every $1 of revenue lost · operating margin -969.8%

Xenon Pharmaceuticals made $7.5M in Q1 2025. Operating margin -969.8%, net loss $65.0M. See where every dollar goes — costs, profit and cash — as a Sankey from the 10-Q filed May 12, 2025.

Revenue$7.5M
Year over year—
Operating margin-969.8%
Net earnings−$65.0M
Operating cash flow−$61.7M

Drawing the Sankey…

Open the interactive Sankey → click any line for what the company wrote about it, compare Y/Y and Q/Q, export as PNG or PDF

What changed this quarter

Revenue was $7.5M in Q1 2025.

Operating costs exceeded revenue by $72.7M, an operating margin of -969.8%. The quarter ended with a net loss of $65.0M.

Operating cash flow was −$61.7M. Non-cash charges added back $659K of depreciation and amortization and $12.2M of share-based compensation. Working capital and other items used $9.4M. Capital expenditures of $43K exceeded it, leaving free cash flow of −$61.7M.

Quarterly history

QuarterFormFiledRevenueY/YOp. marginNet earningsOp. cash flow
Q1 202510-QMay 12, 2025$7.5M—-969.8%−$65.0M−$61.7M

Charts

Xenon Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q2 2026Xenon Pharmaceuticals: where the cash came from (+) and went (−), TTM to Q2 2026Other financing$950MOther investing−$636MOperating cash flow−$338MCash drawn (+) / kept (−)$15.9MShares issued$9.3MCapital spending−$1.0MExchange rates$22K
From the cash-flow statement as filed (SEC XBRL). Cash is fungible: the bars do not say which dollar paid for what.
Xenon Pharmaceuticals: profit against cash, quarter by quarterXenon Pharmaceuticals: profit against cash, quarter by quarterNet incomeOperating cash flow−$62.8M−$49.7MQ3 2024−$65.7M−$54.4MQ4 2024−$65.0M−$61.7MQ1 2025−$84.7M−$64.2MQ2 2025−$90.9M−$71.8MQ3 2025−$105M−$81.5MQ4 2025−$102M−$88.9MQ1 2026−$111M−$95.4MQ2 2026
Latest (Q2 2026): Net income −$111M, Operating cash flow −$95.4M.
Xenon Pharmaceuticals: diluted shares by fiscal yearXenon Pharmaceuticals: diluted shares by fiscal year35MFY202044MFY202161MFY202267MFY202378MFY202479MFY2025
+129.4% since FY2020: more shares outstanding (issuance, stock pay).

Interactive views

The same charts as the app — open one to draw it.

💵Where each $1 goesinteractive

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🌏Named in Asian annual reportsinteractive

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🔄Rotation against the market and its industry (RRG)interactive

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🔍Earnings qualityinteractive

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⚖️Fair value by methodinteractive

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🔭Outlook & guidanceinteractive

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📈Investments: gains and what it boughtinteractive

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🏭Its industry’s money flow (input-output)interactive

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Customers and suppliers named in filings

Sells to

About Xenon Pharmaceuticals

We are a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development and commercialization of life-changing therapeutics for patients in need. We are advancing a differentiated product pipeline led by our investigational candidate, azetukalner, which is being studied in multiple Phase 3 studies in epilepsy, major depressive disorder, or MDD, and bipolar depression, or BPD. Our early-stage pipeline includes Kv7 potassium channel openers and Nav sodium channel modulators being advanced for select high‑need indications, including pain.

In its own words, from its 10-K, filed Feb 26, 2026.

Xenon Pharmaceuticals against its Pharmaceutical Preparations peers

The largest companies of the same SEC industry, each at its latest quarter. Operating margin: -969.8% against the peers' median 20.4%.

CompanyQuarterRevenueY/YOp. margin
XENE Xenon PharmaceuticalsQ1 2025$7.5M—-969.8%
JNJ Johnson & JohnsonQ3 2026$25.4B+6%0.1%
LLY ELI LillyQ3 2026$24.4B+39%34.5%
MRK MerckQ3 2026$18.1B+5%30.7%
ABBV AbbVieQ3 2026$17.4B+10%36.0%
PFE PfizerQ3 2026$16.6B-0.4%20.4%
BMY Bristol Myers SquibbQ3 2026$13.1B+7%19.4%
ABT Abbott LaboratoriesQ3 2026$13.0B+14%10.4%
REGN Regeneron PharmaceuticalsQ3 2026$5.1B+36%40.0%

Source: Xenon Pharmaceuticals 10-Q on SEC EDGAR · CIK 1582313 · Pharmaceutical Preparations

13F: who owns XENE and who is buying

Largest holders of XENE (13F)Largest holders of XENE (13F)FMR LLC$582MBlackRock$454MAvoro Capital Advisors LLC$349MPolar Capital Holdings$276MDriehaus Capital Management LLC$267MJupiter Topco LLC$253MJanus Henderson Group$243MPrice T Rowe Associates$196MCapital International Investors$143MT. Rowe Price Investment Manageme…$131M
Funds' net buying of XENE by quarter (13F)Funds' net buying of XENE by quarter (13F)−$104M2024-09$77.7M2024-12$25.8M2025-03$178M2025-06$31.4M2025-09$51.5M2025-12$941M2026-03$11.4M2026-06
Value of shares 13F filers added minus the value they sold, each quarter (quarters with most filings in).

More on XENE

History

Every quarter: Q1 2025 results

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