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Xilio Therapeutics (XLO) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 8, 2025

Xilio Therapeutics (XLO) reported revenue of $2.9M for the first quarter 2025 (Q1 2025) and +70% from the quarter before. Operating margin was -472.7%, net loss $13.3M (452.7% of revenue).

Revenue$2.9M
Year over year—
Quarter over quarter+70%
Operating margin-472.7%
Net earnings−$13.3M

Xilio Therapeutics, Q1 2025: revenue $2.9M, operating margin -472.7%, net loss $13.3M, operating cash flow $29.0M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$2.9M+70%—
Operating profit−$13.9M——
Net earnings−$13.3M——
Operating cash flow$29.0M——
Free cash flow$29.0M——

What changed

Revenue was $2.9M in Q1 2025, up 70% from the previous quarter.

Operating costs exceeded revenue by $13.9M, an operating margin of -472.7%. The quarter ended with a net loss of $13.3M, wider than the previous quarter's $13.1M loss.

Operating cash flow was $29.0M. Non-cash charges added back $497K of depreciation and amortization and $1.5M of share-based compensation. Working capital and other items added $40.2M. Capital expenditures of $22K left free cash flow of $29.0M.

Questions

What was Xilio Therapeutics' revenue in the first quarter 2025?

Xilio Therapeutics (XLO) reported revenue of $2.9M for the first quarter 2025 (Q1 2025) and +70% from the quarter before.

Was Xilio Therapeutics profitable in the first quarter 2025?

Operating loss was $13.9M (-472.7% of revenue) and net loss $13.3M.

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Source: Xilio Therapeutics 10-Q on SEC EDGAR.