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Filing Flows › Xilio Therapeutics (XLO) › Q1 2026 › vs Q4 2025

Xilio Therapeutics (XLO) Q1 2026 vs Q4 2025 (quarter over quarter)

Xilio Therapeutics's revenue fell $1.0M (-8%) from $13.7M in Q4 2025 to $12.6M in Q1 2026.

Xilio Therapeutics, Q1 2026: revenue $12.6M (+332% year over year), operating margin -111.6%, net loss $9.5M, operating cash flow −$22.3M. The chart draws each line against Q4 2025, the increases inside each band.

Xilio Therapeutics: what changed, Q1 2026 vs Q4 2025Xilio Therapeutics: what changed, Q1 2026 vs Q4 2025Cash used in operations$20.3MNet loss$19.9MNet loss absorbed$19.9MOperating cash sources$19.6MOther income, net−$17.6MCosts & expenses−$9.1MResearch & development$1.7MOperating costs$1.2MShare-based compensation−$719KGeneral & admin−$472K

Every line

LineQ1 2026Q4 2025Change%
Revenue$12.6M$13.7M−$1.0M-8%
Other income, net$4.6M$22.2M−$17.6M-79%
Net loss$9.5M−$10.4M$19.9M—
Costs & expenses$26.8M$35.9M−$9.1M-25%
Operating costs$26.8M$25.5M$1.2M+5%
Research & development$19.8M$18.1M$1.7M+9%
General & admin$6.9M$7.4M−$472K-6%
Operating cash sources$24.9M$5.3M$19.6M+374%
Depreciation & amortization$344K$323K$21K+7%
Share-based compensation$2.2M$2.9M−$719K-25%
Cash used in operations$22.3M$2.0M$20.3M11×
Net loss absorbed$9.5M−$10.4M$19.9M—
Working capital & other$15.4M$15.6M−$242K-2%

Questions

How much did Xilio Therapeutics's revenue grow quarter over quarter in Q1 2026?

Xilio Therapeutics's revenue fell $1.0M (-8%) from $13.7M in Q4 2025 to $12.6M in Q1 2026.

Q1 2026 results → · Compare in the interactive Sankey →