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22nd Century Group (XXII) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 26, 2026

22nd Century Group (XXII) reported revenue of $3.5M for the fourth quarter 2025 (Q4 2025), -12% from a year earlier and -12% from the quarter before. Operating margin was -79.2%, net loss $2.8M (79.4% of revenue).

Revenue$3.5M
Year over year-12%
Quarter over quarter-12%
Operating margin-79.2%
Net earnings−$2.8M

22nd Century Group, Q4 2025: revenue $3.5M (-12% year over year), operating margin -79.2%, net loss $2.8M, operating cash flow $2.7M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$3.5M-12%-12%
Operating profit−$2.8M——
Net earnings−$2.8M-151%—
Operating cash flow$2.7M——
Free cash flow$2.7M——

What changed

Revenue was $3.5M in Q4 2025, down 12% year over year and down 12% from the previous quarter. Contract Manufacturing was the largest line at 96% of revenue.

Operating costs exceeded revenue by $2.8M, an operating margin of -79.2%. Total costs fell 22% while revenue fell 12%. The quarter ended with a net loss of $2.8M, after a profit of $5.5M the previous quarter.

Operating cash flow was $2.7M. Non-cash charges added back $218K of depreciation and amortization and $196K of share-based compensation. Working capital and other items added $5.1M. Capital expenditures of $16K left free cash flow of $2.7M.

Questions

What was 22nd Century Group's revenue in the fourth quarter 2025?

22nd Century Group (XXII) reported revenue of $3.5M for the fourth quarter 2025 (Q4 2025), -12% from a year earlier and -12% from the quarter before.

Was 22nd Century Group profitable in the fourth quarter 2025?

Operating loss was $2.8M (-79.2% of revenue) and net loss $2.8M.

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Source: 22nd Century Group 10-K on SEC EDGAR.