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Zai Lab (ZLAB) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 6, 2025

Zai Lab (ZLAB) reported revenue of $116M for the third quarter 2025 (Q3 2025), +14% from a year earlier and +6% from the quarter before. Operating margin was -42.1%, net loss $36.0M (31.0% of revenue).

Revenue$116M
Year over year+14%
Quarter over quarter+6%
Operating margin-42.1%
Net earnings−$36.0M

Zai Lab, Q3 2025: revenue $116M (+14% year over year), operating margin -42.1%, net loss $36.0M, operating cash flow −$32.0M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$116M+6%+14%
Operating profit−$48.8M——
Net earnings−$36.0M——
Operating cash flow−$32.0M——

What changed

Revenue was $116.1M in Q3 2025, up 14% year over year and up 6% from the previous quarter. ZEJULA was the largest line at 37% of revenue. NUZYRA added $5.4M year over year (up 54%), 39% of the total change. ZEJULA declined 12%.

Operating costs exceeded revenue by $48.8M, an operating margin of -42.1%. Total costs fell 3% while revenue rose 14%. The fastest-growing cost line was Cost of revenue (+28%). The quarter ended with a net loss of $36.0M, narrower than the previous quarter's $40.7M loss. Non-operating items added $12.9M, -36% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$32.0M. Non-cash charges added back $3.9M of depreciation and amortization and $16.9M of share-based compensation. Working capital and other items used $16.9M. Capital expenditures of $3.0M exceeded it, leaving free cash flow of −$35.0M.

Questions

What was Zai Lab's revenue in the third quarter 2025?

Zai Lab (ZLAB) reported revenue of $116M for the third quarter 2025 (Q3 2025), +14% from a year earlier and +6% from the quarter before.

Was Zai Lab profitable in the third quarter 2025?

Operating loss was $48.8M (-42.1% of revenue) and net loss $36.0M.

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Source: Zai Lab 10-Q on SEC EDGAR.