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Zevra Therapeutics (ZVRA) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 9, 2026

Zevra Therapeutics (ZVRA) reported revenue of $34.1M for the fourth quarter 2025 (Q4 2025), +183% from a year earlier and +31% from the quarter before. Operating margin was 27.3%, net earnings $12.2M (35.6% of revenue).

Revenue$34.1M
Year over year+183%
Quarter over quarter+31%
Operating margin27.3%
Net earnings$12.2M

Zevra Therapeutics, Q4 2025: revenue $34.1M (+183% year over year), operating margin 27.3%, net earnings $12.2M, operating cash flow $5.5M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$34.1M+31%+183%
Operating profit$9.3M+125%—
Net earnings$12.2M——
Operating cash flow$5.5M+17%—

What changed

Revenue was $34.1M in Q4 2025, up 183% year over year and up 31% from the previous quarter.

Operating profit was $9.3M, a 27.3% margin (up 155.3 points year over year). Total costs fell 10% while revenue rose 183%. The fastest-growing cost line was SG&A (+26%). Net earnings were $12.2M. The effective tax rate was 4.0%. Non-operating items added $3.4M, 26% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $5.5M, 45% of net earnings. Non-cash charges added back $362K of depreciation and amortization and $4.3M of share-based compensation. Working capital and other items used $11.3M. Capital expenditures of −$31K left free cash flow of $5.5M.

Questions

What was Zevra Therapeutics' revenue in the fourth quarter 2025?

Zevra Therapeutics (ZVRA) reported revenue of $34.1M for the fourth quarter 2025 (Q4 2025), +183% from a year earlier and +31% from the quarter before.

Was Zevra Therapeutics profitable in the fourth quarter 2025?

Operating profit was $9.3M (27.3% of revenue) and net earnings $12.2M.

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Source: Zevra Therapeutics 10-K on SEC EDGAR.