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Zymeworks (ZYME) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 8, 2025

Zymeworks (ZYME) reported revenue of $27.1M for the first quarter 2025 (Q1 2025), +170% from a year earlier and -13% from the quarter before. Operating margin was -94.5%, net loss $22.6M (83.5% of revenue).

Revenue$27.1M
Year over year+170%
Quarter over quarter-13%
Operating margin-94.5%
Net earnings−$22.6M

Zymeworks, Q1 2025: revenue $27.1M (+170% year over year), operating margin -94.5%, net loss $22.6M, operating cash flow −$3.4M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$27.1M-13%+170%
Operating profit−$25.6M——
Net earnings−$22.6M——
Operating cash flow−$3.4M——

What changed

Revenue was $27.1M in Q1 2025, up 170% year over year and down 13% from the previous quarter.

Operating costs exceeded revenue by $25.6M, an operating margin of -94.5%. Total costs grew 10% against revenue growth of 170%. The fastest-growing cost line was Research & development (+12%). The quarter ended with a net loss of $22.6M, narrower than the previous quarter's $23.5M loss.

Operating cash flow was −$3.4M. Non-cash charges added back $2.6M of depreciation and amortization and $6.4M of share-based compensation. Working capital and other items added $10.2M. Capital expenditures of $16K exceeded it, leaving free cash flow of −$3.4M.

Questions

What was Zymeworks' revenue in the first quarter 2025?

Zymeworks (ZYME) reported revenue of $27.1M for the first quarter 2025 (Q1 2025), +170% from a year earlier and -13% from the quarter before.

Was Zymeworks profitable in the first quarter 2025?

Operating loss was $25.6M (-94.5% of revenue) and net loss $22.6M.

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Source: Zymeworks 10-Q on SEC EDGAR.