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Zymeworks (ZYME) Q3 2026 earnings results (third quarter 2026)

10-Q filed Nov 9, 2026

Zymeworks (ZYME) reported revenue of $256M for the third quarter 2026 (Q3 2026), +829% from a year earlier and up 56-fold from the quarter before. Operating margin was 69.2%, net earnings $174M (67.7% of revenue).

Revenue$256M
Year over year+829%
Quarter over quarter56×
Operating margin69.2%
Net earnings$174M

Zymeworks, Q3 2026: revenue $256M (+829% year over year), operating margin 69.2%, net earnings $174M, operating cash flow −$24.0M. The chart follows the revenue to costs, profit and cash.

Q3 2026AmountQ/QY/Y
Revenue$256M56×+829%
Operating profit$178M——
Net earnings$174M——
Operating cash flow−$24.0M——

What changed

Revenue was $256.5M in Q3 2026, up 829% year over year and up 5487% from the previous quarter. License and milestone revenue was the largest line at 97% of revenue. License and milestone revenue added $224.8M year over year (up 890%), 98% of the total change.

Operating profit was $177.6M, a 69.2% margin (up 149.3 points year over year). Total costs grew 59% against revenue growth of 829%. The fastest-growing cost line was SG&A (+202%). Net earnings were $173.7M. The effective tax rate was -0.3%.

Operating cash flow was −$24.0M. Non-cash charges added back $1.7M of depreciation and amortization and $23.1M of share-based compensation. Working capital and other items used $222.5M. Capital expenditures of $73K exceeded it, leaving free cash flow of −$24.1M.

Questions

What was Zymeworks' revenue in the third quarter 2026?

Zymeworks (ZYME) reported revenue of $256M for the third quarter 2026 (Q3 2026), +829% from a year earlier and up 56-fold from the quarter before.

Was Zymeworks profitable in the third quarter 2026?

Operating profit was $178M (69.2% of revenue) and net earnings $174M.

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Source: Zymeworks 10-Q on SEC EDGAR.