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Who owns Zymeworks (ZYME) stock

190 funds reported Zymeworks (ZYME) shares in their latest 13F filings, worth $1.8B in all. The largest holder is EcoR1 Capital, LLC ($600M). Last quarter 76 funds added to their stakes and 97 cut them.

Largest holders of ZYME (13F)Largest holders of ZYME (13F)EcoR1 Capital, LLC$600MRubric Capital Management LP$183MBlackRock$111MPerceptive Advisors LLC$109MBVF$95.4MVanguard Group$61.3MMorgan Stanley$58.3MBNP Paribas Asset Management Hold…$46.6MVanguard Capital Management LLC$40.8MAssenagon Asset Management S.A.$39.9M

Largest holders (13F)

FundSharesValueChangeQuarter
EcoR1 Capital, LLC22,970,388$600Munchanged2026-06-30
Rubric Capital Management LP7,000,000$183Munchanged2026-06-30
BlackRock4,251,030$111Mdecrease2026-06-30
Perceptive Advisors LLC4,182,953$109Mincrease2026-06-30
BVF3,649,142$95.4Mdecrease2026-06-30
Vanguard Group2,328,727$61.3Mincrease2025-12-31
Morgan Stanley2,231,260$58.3Mdecrease2026-06-30
BNP Paribas Asset Management Holding S.A.1,781,116$46.6Mdecrease2026-06-30
Vanguard Capital Management LLC1,558,998$40.8Mdecrease2026-06-30
Assenagon Asset Management S.A.1,508,069$39.9Mdecrease2026-09-30
Nextech Invest1,113,946$29.1Munchanged2026-06-30
State Street1,088,216$28.4Mincrease2026-06-30
Dimensional Fund Advisors LP994,955$26.0Mdecrease2026-06-30
Citadel Advisors LLC914,136$23.9Mdecrease2026-06-30
Nomura Asset Management International889,802$23.3Mnew2026-06-30

Zymeworks' latest quarter

Zymeworks, Q2 2026: revenue $4.6M (-91% year over year), operating margin -919.0%, net loss $45.0M, operating cash flow −$31.9M. The chart follows the revenue to costs, profit and cash.

Questions

Who owns the most ZYME stock?

By the latest 13F filings: EcoR1 Capital, LLC ($600M); Rubric Capital Management LP ($183M); BlackRock ($111M); Perceptive Advisors LLC ($109M); BVF ($95.4M).

What is the short interest in ZYME?

5,577,540 shares were sold short at the 2026-10-15 settlement, 5.41% of the float.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.