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Agios Pharmaceuticals vs Tango Therapeutics: AGIO and TNGX compared

Agios Pharmaceuticals is the larger company: $55.4M of revenue in its latest quarter (Q3 2026) against $53.8M for Tango Therapeutics (Q3 2025). Tango Therapeutics is growing faster (+364% against +330% a year earlier). Tango Therapeutics is more profitable, with an operating margin of 26.2% against -139.3%.

Agios Pharmaceuticals vs Tango Therapeutics, latest quarterAgios Pharmaceuticals vs Tango Therapeutics, latest quarterAgios Pharmaceuticals (AGIO)Tango Therapeutics (TNGX)Revenue$55.4M$53.8MRevenue growth, Y/Y+330%+364%Operating margin-139.3%26.2%Net margin-117.4%29.5%

Where the money goes: AGIO and TNGX

Agios Pharmaceuticals (AGIO) · Q3 2026

Agios Pharmaceuticals, Q3 2026: revenue $55.4M (+330% year over year), operating margin -139.3%, net loss $65.0M, operating cash flow −$59.2M. The chart follows the revenue to costs, profit and cash.

Tango Therapeutics (TNGX) · Q3 2025

Tango Therapeutics, Q3 2025: revenue $53.8M (+364% year over year), operating margin 26.2%, net earnings $15.9M, operating cash flow −$31.0M. The chart follows the revenue to costs, profit and cash.

Agios Pharmaceuticals (AGIO)Tango Therapeutics (TNGX)
Latest quarterQ3 2026Q3 2025
Revenue$55.4M$53.8M
Revenue growth, Y/Y+330%+364%
Operating margin-139.3%26.2%
Net earnings−$65.0M$15.9M
Net margin-117.4%29.5%
Operating cash flow−$59.2M−$31.0M
Market value$1.9B—
Analysts’ mean target$45.88—

Questions

Which is bigger, Agios Pharmaceuticals or Tango Therapeutics?

Agios Pharmaceuticals is the larger company: $55.4M of revenue in its latest quarter (Q3 2026) against $53.8M for Tango Therapeutics (Q3 2025).

Is Agios Pharmaceuticals or Tango Therapeutics growing faster?

Tango Therapeutics is growing faster (+364% against +330% a year earlier).

Which is more profitable, Agios Pharmaceuticals or Tango Therapeutics?

Tango Therapeutics is more profitable, with an operating margin of 26.2% against -139.3%.

More: Agios Pharmaceuticals earnings · how Agios Pharmaceuticals makes money · Tango Therapeutics earnings · how Tango Therapeutics makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 5, 2026; 10-Q filed Nov 4, 2025). Fiscal quarters can end on different dates. Not investment advice.