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Harmony Biosciences Holdings vs Zymeworks: HRMY and ZYME compared
Harmony Biosciences Holdings is the larger company: $269M of revenue in its latest quarter (Q3 2026) against $256M for Zymeworks (Q3 2026). Zymeworks is growing faster (+829% against +12% a year earlier). Zymeworks is more profitable, with an operating margin of 69.2% against 20.2%.
Where the money goes: HRMY and ZYME
Harmony Biosciences Holdings (HRMY) · Q3 2026
Harmony Biosciences Holdings, Q3 2026: revenue $269M (+12% year over year), operating margin 20.2%, net earnings $48.2M, operating cash flow $76.7M. The chart follows the revenue to costs, profit and cash.
Zymeworks (ZYME) · Q3 2026
Zymeworks, Q3 2026: revenue $256M (+829% year over year), operating margin 69.2%, net earnings $174M, operating cash flow −$24.0M. The chart follows the revenue to costs, profit and cash.
| Harmony Biosciences Holdings (HRMY) | Zymeworks (ZYME) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $269M | $256M |
| Revenue growth, Y/Y | +12% | +829% |
| Gross margin | 70.0% | — |
| Operating margin | 20.2% | 69.2% |
| Net earnings | $48.2M | $174M |
| Net margin | 17.9% | 67.7% |
| Operating cash flow | $76.7M | −$24.0M |
| Market value | — | $1.9B |
| Analysts’ mean target | — | $41.50 |
Where the revenue comes from
Zymeworks
- License and milestone revenue: $250M (97%)
- Royalty and other revenue: $4.9M (2%)
- Viatris collaboration agreement revenue: $1.5M (1%)
Questions
Which is bigger, Harmony Biosciences Holdings or Zymeworks?
Harmony Biosciences Holdings is the larger company: $269M of revenue in its latest quarter (Q3 2026) against $256M for Zymeworks (Q3 2026).
Is Harmony Biosciences Holdings or Zymeworks growing faster?
Zymeworks is growing faster (+829% against +12% a year earlier).
Which is more profitable, Harmony Biosciences Holdings or Zymeworks?
Zymeworks is more profitable, with an operating margin of 69.2% against 20.2%.
More: Harmony Biosciences Holdings earnings · how Harmony Biosciences Holdings makes money · Zymeworks earnings · how Zymeworks makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 4, 2026; 10-Q filed Nov 9, 2026). Fiscal quarters can end on different dates. Not investment advice.