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Karyopharm Therapeutics vs Gyre Therapeutics: KPTI and GYRE compared
Karyopharm Therapeutics is the larger company: $33.4M of revenue in its latest quarter (Q2 2026) against $32.9M for Gyre Therapeutics (Q3 2026). Gyre Therapeutics is growing faster (+0.7% against -12% a year earlier). Gyre Therapeutics is more profitable, with an operating margin of -4.6% against -67.4%.
Where the money goes: KPTI and GYRE
Karyopharm Therapeutics (KPTI) · Q2 2026
Karyopharm Therapeutics, Q2 2026: revenue $33.4M (-12% year over year), operating margin -67.4%, net loss $67.0M, operating cash flow −$24.9M. The chart follows the revenue to costs, profit and cash.
Gyre Therapeutics (GYRE) · Q3 2026
Gyre Therapeutics, Q3 2026: revenue $32.9M (+0.7% year over year), operating margin -4.6%, net loss $2.5M, operating cash flow −$4.0M. The chart follows the revenue to costs, profit and cash.
| Karyopharm Therapeutics (KPTI) | Gyre Therapeutics (GYRE) | |
|---|---|---|
| Latest quarter | Q2 2026 | Q3 2026 |
| Revenue | $33.4M | $32.9M |
| Revenue growth, Y/Y | -12% | +0.7% |
| Operating margin | -67.4% | -4.6% |
| Net earnings | −$67.0M | −$2.5M |
| Net margin | -200.5% | -7.5% |
| Operating cash flow | −$24.9M | −$4.0M |
Where the revenue comes from
Karyopharm Therapeutics
- Product: $30.8M (92%)
- License and Other: $2.7M (8%)
Gyre Therapeutics
- Gyre Pharmaceuticals: $32.4M (98%)
- Gyre: $508K (2%)
Questions
Which is bigger, Karyopharm Therapeutics or Gyre Therapeutics?
Karyopharm Therapeutics is the larger company: $33.4M of revenue in its latest quarter (Q2 2026) against $32.9M for Gyre Therapeutics (Q3 2026).
Is Karyopharm Therapeutics or Gyre Therapeutics growing faster?
Gyre Therapeutics is growing faster (+0.7% against -12% a year earlier).
Which is more profitable, Karyopharm Therapeutics or Gyre Therapeutics?
Gyre Therapeutics is more profitable, with an operating margin of -4.6% against -67.4%.
More: Karyopharm Therapeutics earnings · how Karyopharm Therapeutics makes money · Gyre Therapeutics earnings · how Gyre Therapeutics makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Aug 13, 2026; 10-Q filed Nov 6, 2026). Fiscal quarters can end on different dates. Not investment advice.