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Novo Nordisk A S vs AstraZeneca: NVO and AZN compared

Novo Nordisk A S is the larger company: $309.1B of revenue in its latest quarter (FY2025) against $30.7B for AstraZeneca (Q2 2026). AstraZeneca is growing faster (+9% against +6% a year earlier). Novo Nordisk A S is more profitable, with an operating margin of 41.3% against 24.2%.

Novo Nordisk A S vs AstraZeneca, latest quarterNovo Nordisk A S vs AstraZeneca, latest quarterNovo Nordisk A S (NVO)AstraZeneca (AZN)Revenue$309.1B$30.7BRevenue growth, Y/Y+6%+9%Gross margin81.0%83.0%Operating margin41.3%24.2%Net margin33.1%18.2%

Where the money goes: NVO and AZN

Novo Nordisk A S (NVO) · FY2025

Novo Nordisk A S, FY2025: revenue $309.1B (+6% year over year), operating margin 41.3%, net earnings $102.4B, operating cash flow $119.1B. The chart follows the revenue to costs, profit and cash.

AstraZeneca (AZN) · Q2 2026

AstraZeneca, Q2 2026: revenue $30.7B (+9% year over year), operating margin 24.2%, net earnings $5.6B. The chart follows the revenue to costs, profit and cash.

AstraZeneca revenue by segment, Q2 2026AstraZeneca revenue by segment, Q2 2026Oncology$14.1BBioPharmaceuticals$11.2BRare Disease$4.9BOther Medicines$486M
Novo Nordisk A S (NVO)AstraZeneca (AZN)
Latest quarterFY2025Q2 2026
Revenue$309.1B$30.7B
Revenue growth, Y/Y+6%+9%
Gross margin81.0%83.0%
Operating margin41.3%24.2%
Net earnings$102.4B$5.6B
Net margin33.1%18.2%
Operating cash flow$119.1B—
Free cash flow$59.0B—
Market value$186.0B—
P/E1.8×—
Analysts’ mean target$45.56—

Where the revenue comes from

AstraZeneca

Questions

Which is bigger, Novo Nordisk A S or AstraZeneca?

Novo Nordisk A S is the larger company: $309.1B of revenue in its latest quarter (FY2025) against $30.7B for AstraZeneca (Q2 2026).

Is Novo Nordisk A S or AstraZeneca growing faster?

AstraZeneca is growing faster (+9% against +6% a year earlier).

Which is more profitable, Novo Nordisk A S or AstraZeneca?

Novo Nordisk A S is more profitable, with an operating margin of 41.3% against 24.2%.

More: Novo Nordisk A S earnings · how Novo Nordisk A S makes money · AstraZeneca earnings · how AstraZeneca makes money

From the companies' latest 10-Q, 10-K or earnings release (20-F filed Feb 4, 2026; 6-K filed Jul 27, 2026). Fiscal quarters can end on different dates. Not investment advice.