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Septerna vs Verastem: SEPN and VSTM compared
Septerna is the larger company: $26.7M of revenue in its latest quarter (Q2 2026) against $24.0M for Verastem (Q3 2026). Septerna is growing faster (225× against +114% a year earlier). Septerna is more profitable, with an operating margin of -62.9% against -313.3%.
Where the money goes: SEPN and VSTM
Septerna (SEPN) · Q2 2026
Septerna, Q2 2026: revenue $26.7M (225× year over year), operating margin -62.9%, net loss $13.0M, operating cash flow −$22.2M. The chart follows the revenue to costs, profit and cash.
Verastem (VSTM) · Q3 2026
Verastem, Q3 2026: revenue $24.0M (+114% year over year), operating margin -313.3%, net loss $74.7M, operating cash flow −$33.6M. The chart follows the revenue to costs, profit and cash.
| Septerna (SEPN) | Verastem (VSTM) | |
|---|---|---|
| Latest quarter | Q2 2026 | Q3 2026 |
| Revenue | $26.7M | $24.0M |
| Revenue growth, Y/Y | 225× | +114% |
| Operating margin | -62.9% | -313.3% |
| Net earnings | −$13.0M | −$74.7M |
| Net margin | -48.7% | -311.2% |
| Operating cash flow | −$22.2M | −$33.6M |
| Market value | — | $839M |
| Analysts’ mean target | — | $17.22 |
Questions
Which is bigger, Septerna or Verastem?
Septerna is the larger company: $26.7M of revenue in its latest quarter (Q2 2026) against $24.0M for Verastem (Q3 2026).
Is Septerna or Verastem growing faster?
Septerna is growing faster (225× against +114% a year earlier).
Which is more profitable, Septerna or Verastem?
Septerna is more profitable, with an operating margin of -62.9% against -313.3%.
More: Septerna earnings · how Septerna makes money · Verastem earnings · how Verastem makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Aug 10, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.