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Stoke Therapeutics vs Lexicon Pharmaceuticals: STOK and LXRX compared

Stoke Therapeutics is the larger company: $11.3M of revenue in its latest quarter (Q3 2026) against $11.2M for Lexicon Pharmaceuticals (Q3 2026). Stoke Therapeutics is growing faster (+6% against -21% a year earlier). Lexicon Pharmaceuticals is more profitable, with an operating margin of -128.8% against -686.9%.

Stoke Therapeutics vs Lexicon Pharmaceuticals, latest quarterStoke Therapeutics vs Lexicon Pharmaceuticals, latest quarterStoke Therapeutics (STOK)Lexicon Pharmaceuticals (LXRX)Revenue$11.3M$11.2MRevenue growth, Y/Y+6%-21%Operating margin-686.9%-128.8%Net margin-654.3%-124.5%

Where the money goes: STOK and LXRX

Stoke Therapeutics (STOK) · Q3 2026

Stoke Therapeutics, Q3 2026: revenue $11.3M (+6% year over year), operating margin -686.9%, net loss $73.6M, operating cash flow −$62.7M. The chart follows the revenue to costs, profit and cash.

Lexicon Pharmaceuticals (LXRX) · Q3 2026

Lexicon Pharmaceuticals, Q3 2026: revenue $11.2M (-21% year over year), operating margin -128.8%, net loss $14.0M, operating cash flow −$8.1M. The chart follows the revenue to costs, profit and cash.

Stoke Therapeutics (STOK)Lexicon Pharmaceuticals (LXRX)
Latest quarterQ3 2026Q3 2026
Revenue$11.3M$11.2M
Revenue growth, Y/Y+6%-21%
Operating margin-686.9%-128.8%
Net earnings−$73.6M−$14.0M
Net margin-654.3%-124.5%
Operating cash flow−$62.7M−$8.1M

Questions

Which is bigger, Stoke Therapeutics or Lexicon Pharmaceuticals?

Stoke Therapeutics is the larger company: $11.3M of revenue in its latest quarter (Q3 2026) against $11.2M for Lexicon Pharmaceuticals (Q3 2026).

Is Stoke Therapeutics or Lexicon Pharmaceuticals growing faster?

Stoke Therapeutics is growing faster (+6% against -21% a year earlier).

Which is more profitable, Stoke Therapeutics or Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals is more profitable, with an operating margin of -128.8% against -686.9%.

More: Stoke Therapeutics earnings · how Stoke Therapeutics makes money · Lexicon Pharmaceuticals earnings · how Lexicon Pharmaceuticals makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 3, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.