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Vertex Pharmaceuticals vs Zoetis: VRTX and ZTS compared
Vertex Pharmaceuticals is the larger company: $3.4B of revenue in its latest quarter (Q3 2026) against $2.4B for Zoetis (Q3 2026). Vertex Pharmaceuticals is growing faster (+12% against -1% a year earlier). Zoetis is more profitable, with an operating margin of 30.5% against 20.7%.
Where the money goes: VRTX and ZTS
Vertex Pharmaceuticals (VRTX) · Q3 2026
Vertex Pharmaceuticals, Q3 2026: revenue $3.4B (+12% year over year), operating margin 20.7%, net earnings $654M, operating cash flow $643M. The chart follows the revenue to costs, profit and cash.
Zoetis (ZTS) · Q3 2026
Zoetis, Q3 2026: revenue $2.4B (-1% year over year), operating margin 30.5%, net earnings $591M, operating cash flow $824M. The chart follows the revenue to costs, profit and cash.
| Vertex Pharmaceuticals (VRTX) | Zoetis (ZTS) | |
|---|---|---|
| Latest quarter | Q3 2026 | Q3 2026 |
| Revenue | $3.4B | $2.4B |
| Revenue growth, Y/Y | +12% | -1% |
| Operating margin | 20.7% | 30.5% |
| Net earnings | $654M | $591M |
| Net margin | 19.0% | 24.7% |
| Operating cash flow | $643M | $824M |
| Free cash flow | $546M | $717M |
| Market value | $139.6B | $32.7B |
| P/E | 35.2× | 13.0× |
| Analysts’ mean target | $592.36 | $89.69 |
Where the revenue comes from
Vertex Pharmaceuticals
- Total CF product revenues, net: $3.3B (95%)
- CASGEVY: $99.2M (3%)
- JOURNAVX: $58.3M (2%)
Zoetis
- Companion Animal: $1.6B (65%)
- Dermatology: $398M (17%)
- Pain and sedation: $200M (8%)
- Swine: $120M (5%)
Questions
Which is bigger, Vertex Pharmaceuticals or Zoetis?
Vertex Pharmaceuticals is the larger company: $3.4B of revenue in its latest quarter (Q3 2026) against $2.4B for Zoetis (Q3 2026).
Is Vertex Pharmaceuticals or Zoetis growing faster?
Vertex Pharmaceuticals is growing faster (+12% against -1% a year earlier).
Which is more profitable, Vertex Pharmaceuticals or Zoetis?
Zoetis is more profitable, with an operating margin of 30.5% against 20.7%.
More: Vertex Pharmaceuticals earnings · how Vertex Pharmaceuticals makes money · Zoetis earnings · how Zoetis makes money
From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Nov 3, 2026; 10-Q filed Nov 5, 2026). Fiscal quarters can end on different dates. Not investment advice.