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Xilio Therapeutics vs Journey Medical: XLO and DERM compared

Xilio Therapeutics is the larger company: $18.7M of revenue in its latest quarter (Q2 2026) against $18.5M for Journey Medical (Q2 2026). Xilio Therapeutics is growing faster (+131% against +23% a year earlier). Journey Medical is more profitable, with an operating margin of 2.5% against -18.7%.

Xilio Therapeutics vs Journey Medical, latest quarterXilio Therapeutics vs Journey Medical, latest quarterXilio Therapeutics (XLO)Journey Medical (DERM)Revenue$18.7M$18.5MRevenue growth, Y/Y+131%+23%Operating margin-18.7%2.5%Net margin-34.1%-1.7%

Where the money goes: XLO and DERM

Xilio Therapeutics (XLO) · Q2 2026

Xilio Therapeutics, Q2 2026: revenue $18.7M (+131% year over year), operating margin -18.7%, net loss $6.4M, operating cash flow −$18.8M. The chart follows the revenue to costs, profit and cash.

Journey Medical (DERM) · Q2 2026

Journey Medical, Q2 2026: revenue $18.5M (+23% year over year), operating margin 2.5%, net loss $312K, operating cash flow −$1.7M. The chart follows the revenue to costs, profit and cash.

Journey Medical revenue by segment, Q2 2026Journey Medical revenue by segment, Q2 2026Emrosi$8.1MQbrexza$5.1MAccutane$3.4MFoam franchise products (Amzeeq &…$941K
Xilio Therapeutics (XLO)Journey Medical (DERM)
Latest quarterQ2 2026Q2 2026
Revenue$18.7M$18.5M
Revenue growth, Y/Y+131%+23%
Operating margin-18.7%2.5%
Net earnings−$6.4M−$312K
Net margin-34.1%-1.7%
Operating cash flow−$18.8M−$1.7M

Where the revenue comes from

Journey Medical

Questions

Which is bigger, Xilio Therapeutics or Journey Medical?

Xilio Therapeutics is the larger company: $18.7M of revenue in its latest quarter (Q2 2026) against $18.5M for Journey Medical (Q2 2026).

Is Xilio Therapeutics or Journey Medical growing faster?

Xilio Therapeutics is growing faster (+131% against +23% a year earlier).

Which is more profitable, Xilio Therapeutics or Journey Medical?

Journey Medical is more profitable, with an operating margin of 2.5% against -18.7%.

More: Xilio Therapeutics earnings · how Xilio Therapeutics makes money · Journey Medical earnings · how Journey Medical makes money

From the companies' latest 10-Q, 10-K or earnings release (10-Q filed Aug 12, 2026; 10-Q filed Aug 12, 2026). Fiscal quarters can end on different dates. Not investment advice.