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Merck & Co.: 13F portfolio Q2 2026 and what copying it returned

Merck & Co.'s 13F for the quarter ended 2026-06-30 (filed Aug 7, 2026): 13 common-share positions, $526M reported. Copying each 13F the day after it was filed returned +477.0% from May 16, 2025 to Nov 6, 2026, against +24.5% for SPY.

Reported 13F assets$526M
Positions (common)13
Quarter2026-06-30
Clone return+477.0%
SPY, same days+24.5%
Clone max drawdown-29.0%

Copying the 13F

2025-052025-082025-112026-022026-052026-082026-11cloneSPY

Each 13F bought at the close of the first trading day after it was filed and held, drifting, until the next one; value-weighted over the common-share positions with a price (91.4% of the portfolio on average); 6 filings since May 14, 2025. Price returns for the clone and SPY alike (no dividends, no costs). A 13F lists only US long positions at quarter end, reported up to 45 days later.

Largest holdings (2026-06-30)

Merck & Co.: largest 13F holdings, 2026-06-30Merck & Co.: largest 13F holdings, 2026-06-30PSNL · Personalis$188MMRNA · Moderna$162MKYMR · Kymera Therapeutics$88.5MAKTS · Aktis Oncology$30.7MEIKN · Eikon Therapeutics$21.7MTRDA · Entrada Therapeutics$12.8MSTRO · Sutro Biopharma$9.0MALEC · Alector$7.1MEVAX · Evaxion A/S$3.8MVRDN · Viridian Therapeutics$1.7MXLO · Xilio Therapeutics$1.0MHURA · TuHURA Biosciences$46KNEUP · Neuphoria Therapeutics$44K
TickerCompanyWeightValueChange in the quarter
PSNLPersonalis35.8%$188Munchanged
MRNAModerna30.7%$162Munchanged
KYMRKymera Therapeutics16.8%$88.5Munchanged
AKTSAktis Oncology5.8%$30.7Munchanged
EIKNEikon Therapeutics4.1%$21.7Munchanged
TRDAEntrada Therapeutics2.4%$12.8Mnew
STROSutro Biopharma1.7%$9.0Mnew
ALECAlector1.4%$7.1Munchanged
EVAXEvaxion A/S0.7%$3.8Mnew
VRDNViridian Therapeutics0.3%$1.7Munchanged
XLOXilio Therapeutics0.2%$1.0Munchanged
HURATuHURA Biosciences0.0%$46Kunchanged
NEUPNeuphoria Therapeutics0.0%$44Kunchanged

Biggest adds

Biggest cuts

Track record

Of 7 position changes scored in 7 separate decisions, 57.1% were on the right side of SPY over the next three months (Disclosures → Smart money).

Open in Disclosures → every quarter, the clone month by month, the smart-money record

Source: SEC Form 13F-HR, filer CIK 310158. Not investment advice.