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Amgen (AMGN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 13, 2026

Amgen (AMGN) reported revenue of $9.9B for the fourth quarter 2025 (Q4 2025), +9% from a year earlier and +3% from the quarter before. Operating margin was 27.6%, net earnings $1.3B (13.5% of revenue).

Revenue$9.9B
Year over year+9%
Quarter over quarter+3%
Operating margin27.6%
Net earnings$1.3B

Amgen, Q4 2025: revenue $9.9B (+9% year over year), operating margin 27.6%, net earnings $1.3B, operating cash flow $1.6B. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$9.9B+3%+9%
Operating profit$2.7B+8%+18%
Net earnings$1.3B-59%+113%
Operating cash flow$1.6B-66%-66%
Free cash flow$1.0B—-77%

What changed

Revenue was $9.9B in Q4 2025, up 9% year over year and up 3% from the previous quarter. Product sales was the largest line at 95% of revenue.

Operating profit was $2.7B, a 27.6% margin (up 2.1 points year over year). Of the extra revenue versus a year earlier, 52% reached operating profit, above the 25% margin then. Total costs grew 5% against revenue growth of 9%. The fastest-growing cost line was Other operating costs (+25%). Net earnings were $1.3B, up 113% year over year. The effective tax rate was 12.0%.

Operating cash flow was $1.6B (down 66% year over year), 120% of net earnings. Non-cash charges added back $1.1B of depreciation and amortization and $0.12B of share-based compensation. Working capital and other items used $1.0B. After capital Expenditures ($0.60B), free cash flow as the company reports it was $1.0B.

Questions

What was Amgen's revenue in the fourth quarter 2025?

Amgen (AMGN) reported revenue of $9.9B for the fourth quarter 2025 (Q4 2025), +9% from a year earlier and +3% from the quarter before.

Was Amgen profitable in the fourth quarter 2025?

Operating profit was $2.7B (27.6% of revenue) and net earnings $1.3B.

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Source: Amgen 10-K on SEC EDGAR.