Filing Flows › Arvinas (ARVN) › Q4 2025
Arvinas (ARVN) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 24, 2026
Arvinas (ARVN) reported revenue of $9.5M for the fourth quarter 2025 (Q4 2025), -84% from a year earlier and -77% from the quarter before. Operating margin was -785.3%, net loss $67.4M (709.5% of revenue).
Arvinas, Q4 2025: revenue $9.5M (-84% year over year), operating margin -785.3%, net loss $67.4M, operating cash flow −$30.4M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $9.5M | -77% | -84% |
| Operating profit | −$74.6M | — | — |
| Net earnings | −$67.4M | — | — |
| Operating cash flow | −$30.4M | — | — |
What changed
Revenue was $9.5M in Q4 2025, down 84% year over year and down 77% from the previous quarter.
Operating costs exceeded revenue by $74.6M, an operating margin of -785.3%. Total costs fell 28% while revenue fell 84%. The quarter ended with a net loss of $67.4M, wider than the previous quarter's $35.1M loss.
Operating cash flow was −$30.4M. Non-cash charges added back $700K of depreciation and amortization and $8.5M of share-based compensation. Working capital and other items added $27.8M. Capital expenditures of $200K exceeded it, leaving free cash flow of −$30.6M.
Questions
What was Arvinas' revenue in the fourth quarter 2025?
Arvinas (ARVN) reported revenue of $9.5M for the fourth quarter 2025 (Q4 2025), -84% from a year earlier and -77% from the quarter before.
Was Arvinas profitable in the fourth quarter 2025?
Operating loss was $74.6M (-785.3% of revenue) and net loss $67.4M.
Source: Arvinas 10-K on SEC EDGAR.