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Avalo Therapeutics (AVTX) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 23, 2026

Avalo Therapeutics (AVTX) reported revenue of $59K for the fourth quarter 2025 (Q4 2025), -69% from a year earlier.

Revenue$59K
Year over year-69%
Quarter over quarter—
Operating margin—
Net earnings−$13.7M

Avalo Therapeutics, Q4 2025: revenue $59K (-69% year over year), net loss $13.7M, operating cash flow −$14.2M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$59K—-69%
Operating profit−$19.7M——
Net earnings−$13.7M——
Operating cash flow−$14.2M——

What changed

Revenue was $59K in Q4 2025, down 69% year over year.

Operating costs exceeded revenue by $19.7M, an operating margin of -33461.0%. Total costs grew 47% against a revenue fall of 69%. The fastest-growing cost line was Research & development (+62%). The quarter ended with a net loss of $13.7M. Non-operating items added $6.2M, -45% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$14.2M. Non-cash charges added back $16K of depreciation and amortization and $4.5M of share-based compensation. Working capital and other items used $5.0M.

Questions

What was Avalo Therapeutics' revenue in the fourth quarter 2025?

Avalo Therapeutics (AVTX) reported revenue of $59K for the fourth quarter 2025 (Q4 2025), -69% from a year earlier.

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Source: Avalo Therapeutics 10-K on SEC EDGAR.